A tetrahydro-benzthiazole of the formula: ##STR18## wherein R.sub.1 is a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, an allyl, benzyl, 2-chloro-benzyl, 4-chloro-benzyl, 3,4-dichloro-benzyl or phenylethyl group; R.sub.2 is a hydrogen atom, a methyl or ethyl group; R.sub.3 is a hydrogen atom, an alkyl group with 1 to 6 carbon atoms, an allyl, propargyl, benzyl, chlorobenzyl, phenylethyl, cyclopentyl or cyclohexyl group; and, R.sub.4 is a hydrogen atom, an alkyl group having 1 to 3 carbon atoms or an allyl group; or, R.sub.3 and R.sub.4 together with the nitrogen atom between them form a piperidino, hexamethyleneimino or morpholino group; or, a pharmaceutically acceptable acid addition salt thereof. view more

A tetrahydro-benzthiazole of formula Ia, as claimed in claim 3 wherein the ##STR19## group is in the 6-position.

A tetrahydro-benzthiazole of formula Ia, as claimed in claim 3, wherein R.sub.1 and R.sub.2 together with the nitrogen atom between them form an amino or allylamino group; and, R.sub.3 and R.sub.4 together with the nitrogen atom between them form a dimethylamino, diethylamino, N-allyl-N-(4-chloro-benzyl)-amino, n- propylamino or group. view more

2-Amino-6-n-propylamino-4,5,6,7-tetrahydro-benzthiazole, or a pharmaceutically acceptable acid addition salt thereof.

A tetrahydrobenzthiazole of the formula ##STR20## wherein R is an alkyl group with 1 to 7 carbon atoms, a cycloalkyl group having 3 to 7 carbon atoms, an alkenyl or alkynyl group having 3 to 6 carbon atoms, an alkanoyl group having 1 to 7 carbon atoms or a phenyl alkyl or phenyl alkanoyl group having 1 to 3 carbon atoms in the alkyl moiets, wherein the phenyl nucleus may be substituted by fluorine, chlorine or bromine atoms. view more

The compound of claim 9 wherein R is an alkyl group having 1 to 7 carbon atoms.