-
PerkinElmer, Inc. et al v. Intema Limited DC CAFC
- 1:09-cv-10176
- D. Mass.
- Judge: F. Dennis Saylor, IV
+1
- Filed: 02/05/2009
- Closed: 09/06/2011
- Latest Docket Entry: 03/05/2013
- PACER
2
Plaintiffs
1
Defendant
0
Accused
Products
1
Patent-in-Suit
944
Days in
Litigation
-
PerkinElmer, Inc. et al v. Intema Limited DC CAFC
- 1:09-cv-10176
- D. Mass.
- Judge: F. Dennis Saylor, IV
+1
- Filed: 02/05/2009
- Closed: 09/06/2011
- Latest Docket Entry: 03/05/2013
- PACER
Market Sector
Medical
Assigned Judge
Previously Presiding
Nancy Gertner (until 12/18/2011)
Outcome Summary
Patent Information
-
Validity & Enforceability
Claim # | Claim Text | Outcome |
---|---|---|
1 |
A method of determining whether a pregnant woman is at an increased risk of having a fetus with Down's syndrome, the method comprising the steps of:</claim-text> measuring the level of at least one screening marker from a first trimester of pregnancy
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|
Invalid (102 and 103)
Entry 277 Entry 280 |
2 |
A method according to claim 1, wherein the step of determining the risk of Down's syndrome comprises deriving the likelihood ratio of Down's syndrome using a multivariate analysis of the measured levels of the screening markers from both the first
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|
Invalid (102 and 103)
Entry 280 |
3 |
A method according to claim 2, wherein said multivariate analysis is a multivariate Gaussian analysis.
|
Invalid (102 and 103)
Entry 280 |
4 |
A method according to claim 2, wherein the step of determining the risk of Down's syndrome further comprises multiplying the likelihood ratio by an age-specific risk.
|
Invalid (102 and 103)
Entry 280 |
5 |
A method according to claim 1, further comprising the step of re-expressing each measured level of a screening marker as a multiple of the median level of the respective screening marker in unaffected pregnancies of the same gestational age as the
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|
Invalid (102 and 103)
Entry 277 Entry 280 |
6 |
A method according to claim 1, further comprising comparing the determined risk with a predetermined cut-off level to classify the pregnant women as screen-positive or screen negative based on the comparison.
|
Invalid (102 and 103)
Entry 277 Entry 280 |
7 |
A method according to claim 1, wherein said step of measuring the level of at least one first screening marker from a first trimester of pregnancy includes assaying a serum sample obtained from the pregnant woman during said first trimester of
view more
|
Invalid (102 and 103)
Entry 280 |
8 |
A method according to claim 7, wherein said step of measuring the level of at least one second screening marker from a second trimester of pregnancy includes assaying a serum sample obtained from the pregnant woman during said second trimester of
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|
Invalid (102 and 103)
Entry 280 |
11 |
A method according to claim 1, further comprising adjusting any or all of the measured levels of the screening markers to allow for one or more factors selected from the group of maternal race, maternal weight, multiple birth and diabetic status.
|
Invalid (102 and 103)
Entry 280 |
12 |
A method according to claim 1, further comprising the steps of:</claim-text> obtaining said sample from the pregnant woman during said first trimester of pregnancy and/or taking said ultrasound scan during said first trimester of pregnancy; and
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|
Invalid (102 and 103)
Entry 277 Entry 280 |
15 |
A method according to claim 1, further comprising:</claim-text> determining a first risk estimate of Down's syndrome using the measured level of the at least one first screening marker from the first trimester of pregnancy; comparing the first risk
view more
|
Invalid (102 and 103)
Entry 277 Entry 280 |
20 |
A method of determining whether a pregnant woman is at an increased risk of having a fetus with Down's syndrome, the method comprising the steps of:</claim-text> measuring the level of at least one first screening marker from a first trimester of
view more
|
Invalid (102 and 103)
Entry 277 Entry 280 |
All Claims |
NA
|
Valid (101)
Entry 277 |