A process for producing on an industrial scale the oxidized coenzyme Q<sub>10 </sub>represented by the following formula:</claim-text> <chemistry id="CHEM-US-00007" num="00007"><img id="EMI-C00007" he="24.38mm" wi="47.50mm" " img-format="tif"/> which comprises culturing reduced coenzyme Q₁₀-producing microorganisms in a culture medium containing a carbon source, a nitrogen source, a phosphorus source and a micronutrient to obtain microbial cells containing reduced coenzyme Q₁₀ at a ratio of not less than 70 mole % among the entire coenzymes Q₁₀, disrupting the microbial cells to obtain reduced coenzyme Q₁₀; and oxidizing thus-obtained reduced coenzyme Q₁₀ to oxidized coenzyme Q₁₀ and then extracting the oxidized coenzyme Q₁₀ by an organic solvent in a sealed tank. view more

A process for producing on an industrial scale the oxidized coenzyme Q<sub>10 </sub>represented by the following formula:</claim-text> <chemistry id="CHEM-US-00008" num="00008"><img id="EMI-C00008" he="24.38mm" wi="47.50mm" " img-format="tif"/> which comprises culturing reduced coenzyme Q₁₀-producing microorganisms in a culture medium containing a carbon source, a nitrogen source, a phosphorus source and a micronutrient to obtain microbial cells containing reduced coenzyme Q₁₀ at a ratio of not less than 70 mole % among the entire coenzymes Q₁₀, extracting the reduced coenzyme Q₁₀ by an organic solvent in a sealed tank, and oxidizing the extracted reduced coenzyme Q₁₀ to oxidized coenzyme Q₁₀. view more