The Federal Circuit has upheld the Patent Trial and Appeal Board’s (PTAB’s) invalidation of a software activation patent asserted by Uniloc Corporation Pty. Limited in more than 65 lawsuits against over 145 defendants (2016-2000). The invalid patent is the NPE’s most widely litigated, in a campaign started 14 years ago. In an October 23 decision, the Federal Circuit affirmed the Board’s holding, in two inter partes reviews, filed by Cambium Learning Group, Kofax, SEGA, and Ubisoft (IPR2014-01453) and Perfect World Entertainment (IPR2015-01026), that the patent at issue was not entitled to the earlier priority date of two Australian provisional applications. The court then declined to overturn the PTAB’s ruling that the patent’s claims are invalid in light of prior art.