Light harvesting multichromophore compositions and methods of using the same
First Claim
1. A labelling composition, comprising:
- a donor light harvesting multichromophore that is a conjugated polymer and upon excitation is capable of transferring energy to an acceptor signaling chromophore; and
the acceptor signaling chromophore that is a fluorescent dye in energy-receiving proximity to the donor light harvesting multichromophore.
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Abstract
Light harvesting luminescent multichromophores that are configured upon excitation to transfer energy to, and amplify the emission from, an acceptor signaling chromophore in energy-receiving proximity therewith are provided. Also provided are compositions for labelling a target. The labelling composition may include a donor light harvesting multichromophore and an acceptor signaling chromophore in energy-receiving proximity to the donor light harvesting multichromophore. Also provided is an aqueous composition for labelling a target, including: a donor light harvesting multichromophore; an acceptor signaling chromophore in energy-receiving proximity therewith; and a sensor biomolecule. Methods for using the subject compositions are also provided.
70 Citations
17 Claims
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1. A labelling composition, comprising:
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a donor light harvesting multichromophore that is a conjugated polymer and upon excitation is capable of transferring energy to an acceptor signaling chromophore; and the acceptor signaling chromophore that is a fluorescent dye in energy-receiving proximity to the donor light harvesting multichromophore. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification