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Anterior segment drug delivery

  • US 10,004,636 B2
  • Filed: 08/05/2016
  • Issued: 06/26/2018
  • Est. Priority Date: 06/03/2009
  • Status: Active Grant
First Claim
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1. An ocular insert for use in an eye, the eye having upper and lower lids extendable along an anterior eye surface with an optical zone therebetween, the insert comprising:

  • a first structure comprising an annulus formed of a non-biodegradable suture having a length disposable along the anterior surface of the eye of a patient sized to fit outside the optical zone of the cornea;

    a second structure completely surrounding the suture such that at least a portion of the length of the suture threads through an interior of the second structure, the second structure cushioning engagement between the insert and the eye so as to inhibit irritation of the eye when the first structure helps maintain the insert in contact with the eye for a plurality of days; and

    at least one drug disposed on or embedded into the second structure so as to release a safe and therapeutically effective quantity of the drug to the eye for each of the plurality of days.

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