Reserve zirconium phosphate module for use in sorbent dialysis
First Claim
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1. A dialysate regeneration system comprising:
- a material capable of converting urea to ammonia from a dialyzed fluid;
a first compartment having at least one sorbent material wherein the at least one sorbent material is capable of removing ammonia or ammonium ions generated from the converted urea from the dialyzed fluid;
a second compartment having at least one sorbent material capable of removing ammonia or ammonium ions generated from the converted urea from the dialyzed fluid;
at least one ammonia detector to detect ammonia breakthrough;
wherein one or more valves are responsive to detected ammonia breakthrough;
the first and second compartment in fluid communication with each other as controlled by the one or more valves positioned to selectively direct the fluid into one of the first and second compartments based on detection of ammonia breakthrough from the other one of the first and second compartments.
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Abstract
A reserve zirconium phosphate module for continuing dialysis in the event the capacity of the original zirconium phosphate module is exceeded. The sorbent cartridge can have a sensor for detecting when the capacity of the zirconium phosphate material has been exceeded, and a valve assembly for diverting the flow of spent dialysate into the reserve module when needed. Any of the modules of the sorbent cartridge can be reusable and the sorbent materials therein recharged.
52 Citations
22 Claims
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1. A dialysate regeneration system comprising:
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a material capable of converting urea to ammonia from a dialyzed fluid; a first compartment having at least one sorbent material wherein the at least one sorbent material is capable of removing ammonia or ammonium ions generated from the converted urea from the dialyzed fluid; a second compartment having at least one sorbent material capable of removing ammonia or ammonium ions generated from the converted urea from the dialyzed fluid; at least one ammonia detector to detect ammonia breakthrough;
wherein one or more valves are responsive to detected ammonia breakthrough;the first and second compartment in fluid communication with each other as controlled by the one or more valves positioned to selectively direct the fluid into one of the first and second compartments based on detection of ammonia breakthrough from the other one of the first and second compartments. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A dialysate regeneration system comprising:
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a sorbent cartridge comprising at least a first compartment and a second compartment positioned in series; the first compartment having at least one sorbent material wherein the at least one sorbent material is capable of removing ammonia or ammonium ions from a fluid; the second compartment having at least one sorbent material capable of removing ammonia or ammonium ions from the fluid; the first and second compartment in fluid communication with each other as controlled by one or more valves positioned on a connector after the first compartment; a bypass line connected to the one or more valves positioned on a connector after the first compartment;
wherein the one or more valves are initially set to direct the fluid into the bypass line and around the second compartment and wherein the one or more valves are switched to direct the fluid into the second compartment based on detection of ammonia breakthrough from the first compartment; andat least one ammonia detector to detect the ammonia breakthrough;
wherein the one or more valves are responsive to the detected ammonia breakthrough. - View Dependent Claims (15, 16, 17, 18, 19)
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20. A method for performing dialysis, comprising:
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determining an amount of ammonia leaving a first compartment capable of removing ammonia or ammonium ions generated from converting urea in a dialyzed fluid from a dialysis fluid using an ammonia sensor; diverting flow of the dialysis fluid from the first compartment to a second compartment capable of removing ammonia or ammonium ions from a fluid based on detection of ammonia breakthrough from the first compartment by the ammonia sensor. - View Dependent Claims (21, 22)
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Specification