Test strips having ceria nanoparticle electrodes
First Claim
1. An electrode assembly for an in vitro electrochemical sensor, the electrode assembly comprising:
- a first electrode comprising an analyte responsive enzyme; and
a second electrode in electrical communication with the first electrode, the second electrode comprising a substrate and a ceria nanoparticle composition applied upon the substrate, the ceria nanoparticle composition having a total mass of ceria nanoparticles per cm2 of substrate area in a range of 0.5 mg/cm2 to 500 mg/cm2.
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Accused Products
Abstract
Ceria nanoparticle compositions for use with in vitro electrochemical chemical or biochemical sensors (e.g., test strip glucose sensors), for example to form a cathode or a reference electrode, are provided. The ceria nanoparticle compositions may be combined with a conductive material (e.g., mixed with) to form the cathode or the reference electrode or the ceria nanoparticle compositions may be deposited over a layer of conductive material to form the cathode or the reference electrode. Electrochemical in vitro sensors for determining the concentration of an analyte having a reference electrode and/or a cathode including a ceria nanoparticle composition, and methods for determining an analyte concentration using the electrochemical sensors are also described. Methods of making in vitro electrochemical sensors having a reference electrode and/or a cathode including a ceria nanoparticle composition are also provided.
93 Citations
31 Claims
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1. An electrode assembly for an in vitro electrochemical sensor, the electrode assembly comprising:
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a first electrode comprising an analyte responsive enzyme; and a second electrode in electrical communication with the first electrode, the second electrode comprising a substrate and a ceria nanoparticle composition applied upon the substrate, the ceria nanoparticle composition having a total mass of ceria nanoparticles per cm2 of substrate area in a range of 0.5 mg/cm2 to 500 mg/cm2. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification