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Stable pharmaceutical composition and methods of using same

  • US 10,010,517 B2
  • Filed: 01/25/2017
  • Issued: 07/03/2018
  • Est. Priority Date: 04/29/2009
  • Status: Active Grant
First Claim
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1. A method of lowering triglycerides in a subject having triglycerides of about 200 mg/dl to less than 500 mg/dl who is receiving statin therapy comprising, administering from 2000 mg to about 5000 mg to the subject daily a pharmaceutical composition comprising at least 96% pure ethyl-EPA for a period of at least about 4 weeks, and wherein the period is effective to lower fasting triglycerides in the subject compared to a fasting triglyceride level in a subject maintained on stable statin therapy without concomitant ethyl-EPA for said period.

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