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System and method for monitoring and treating a surface of a subject

  • US 10,016,164 B2
  • Filed: 07/10/2013
  • Issued: 07/10/2018
  • Est. Priority Date: 07/10/2012
  • Status: Active Grant
First Claim
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1. A device comprising:

  • a sensor configured to detect a concentration of an analyte selected from the group consisting of molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma and tissue, and hydrogen ions;

    a therapeutic portion configured to deliver at least one of a therapeutic agent, a biomarker, and a diagnostic agent to a tissue surface of a patient in response to a stimulus or stimuli selected from the group consisting of chemical, mechanical pressure, light and ultrasound;

    a matrix compatible with said sensor and the therapeutic portion, at least a portion of said matrix is at least one of accessible and permeable to said analyte; and

    a dressing comprising said matrix and said sensor and the therapeutic portion;

    wherein said device emits a signal in response to the concentration of said analyte detected by said sensor by modulation of inelastic scattering of an electromagnetic field, including at least one of phosphorescence, fluorescence, and absorption.

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