Temporary venous filter with anti-coagulant delivery method

• US 10,022,212 B2
• Filed: 01/13/2011
• Issued: 07/17/2018
• Est. Priority Date: 01/13/2011
• Status: Active Grant

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Inventors: Koehler, Cleve
• Primary Examiner(s): STRANSKY, KATRINA MARIE
• Application Number:
  US13/005,957
• Publication Number:
  US 20120184984A1
• Time in Patent Office: 2,742 Days
• Field of Search: 606200, 606191, 606192, 606509, 606 33, 606 12, 606157-159, 128897-899, 604105-109
• CPC Class Codes: A61F 2/0103 With centering means
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body

Abstract

The present invention provides a removable vena cava filter for capturing and treating blood clots in a blood vessel. The filter comprises a hub, a plurality of struts extending distally from the hub, and a tubular member disposed through the hub. The tubular member has a proximal end and a distal portion including a plurality of perforations. A catheter may be attached to the proximal end of the tubular member. Fluid may be injected into the catheter to treat blood clots captured in the filter.

Claims

1. A filter for capturing and treating blood clots in a blood vessel, the filter comprising:

only one hub having a distal end and a proximal end;

a plurality of struts extending distally from the distal end of the hub and having distal strut ends located radially outward from the hub in an expanded configuration; and

a tubular member disposed through the hub, the tubular member having a distal end and a proximal end and extending along a central longitudinal axis when the struts are in the expanded configuration, the tubular member having a distal portion extending from the distal end of the hub to the distal end of the tubular member, an intermediate portion extending through the hub from the proximal end of the hub to the distal end of the hub, and a proximal portion extending from the proximal end of the hub to the proximal end of the tubular member, the distal portion, the intermediate portion, and the proximal portion being in fluid communication via a lumen extending inside the tubular member, the distal portion of the tubular member having a plurality of perforations, and the proximal end being free of perforations and having an opening in communication with the lumen and with the perforations, the opening being located relative to the hub longitudinally opposite the plurality of struts and configured to be sealingly attached to a catheter to place a lumen of the catheter in fluid communication with the lumen of the tubular member, the distal end of the tubular member being closed.

2. The filter of claim 1, wherein the tubular member is fixedly attached to the hub.

3. The filter of claim 1, wherein each strut has a first end attached to the hub and a second end, and wherein the distal end of the tubular member is disposed distally from the second ends of the plurality of struts.

4. The filter of claim 1, wherein the tubular member is constructed from a rigid material.

5. The filter of claim 1, wherein the tubular member is constructed from a flexible material.

6. The filter of claim 1, wherein the perforations are selectively placed on the distal portion of the tubular member.

7. The filter of claim 1, wherein the perforations have a plurality of sizes or shapes.

8. The filter of claim 1, wherein the plurality of struts comprise:

a plurality of primary struts having first ends attached to the hub along a longitudinal axis, each primary strut extending arcuately along the longitudinal axis and linearly radially, each primary strut including an arcuate segment having a first absolute tensile strength, the arcuate segment including a first curved portion and a second curved portion, the first curved portion extending from the first end away from the longitudinal axis, the second curved portion extending from the first curved portion toward the longitudinal axis and terminating at an anchoring hook, the anchoring hook being integral with the arcuate segment and having the same thickness as the arcuate segment; and

a plurality of secondary struts freely spaced between the primary struts and having connected ends attached to the hub along the longitudinal axis, each secondary strut freely extending from the connected end to a free end avoiding contact with other secondary struts and primary struts, each secondary strut extending arcuately along the longitudinal axis and linearly radially, each secondary strut including a first arc and a second arc, the first arc extending from the connected end away from the longitudinal axis, the second arc extending from the first arc toward the longitudinal axis and terminating at the free end without a hook, each secondary strut having a second absolute tensile strength.

9. A filter assembly for capturing and treating blood clots in a blood vessel, the assembly comprising:

a filter comprising;

only one hub having a distal end and a proximal end;

a plurality of struts extending distally from the distal end of the hub and having distal strut ends located radially outward from the hub in an expanded configuration; and

a tubular member disposed through the hub, the tubular member having a distal end and a proximal end and extending along a central longitudinal axis when the struts are in the expanded configuration; and

the tubular member having a distal portion extending from the distal end of the hub to the distal end of the tubular member, an intermediate portion extending through the hub from the proximal end of the hub to the distal end of the hub, and a proximal portion extending from the proximal end of the hub to the proximal end of the tubular member, the distal portion, the intermediate portion, and the proximal portion being in fluid communication via a lumen extending inside the tubular member, the distal portion of the tubular member having a plurality of perforations, and the proximal end having an opening in communication with the lumen and with the perforations, wherein the proximal portion is free of perforations, the distal end of the tubular member being closed; and

a catheter in fluid communication with the lumen of the tubular member, the catheter having a distal end and a proximal end, the distal end of the catheter sealingly adjoining the proximal end of the tubular member, the proximal end of the tubular member being located relative to the hub longitudinally opposite the plurality of struts.

10. The filter assembly of claim 9, wherein the distal end of the catheter is fixedly attached to the proximal end of the tubular member.

11. The filter assembly of claim 9, wherein the catheter is formed integrally with the tubular member.

12. The filter assembly of claim 9, wherein the catheter is constructed from a flexible material.

13. The filter assembly of claim 9, further comprising a fluid manifold attached to the proximal end of the catheter.

14. A method for capturing and treating blood clots in a blood vessel, the method comprising the steps of:

deploying a filter assembly in the blood vessel, the filter assembly comprising;

a filter comprising;

only one hub having a distal end and a proximal end;

a plurality of struts extending distally from the distal end of the hub and having distal strut ends located radially outward from the hub in an expanded configuration; and

a tubular member passing through the hub, the tubular member having a distal end and a proximal end and extending along a central longitudinal axis when the struts are in the expanded configuration, the tubular member having a distal portion extending from the distal end of the hub to the distal end of the tubular member, an intermediate portion extending through the hub from the proximal end of the hub to the distal end of the hub, and a proximal portion extending from the proximal end of the hub to the proximal end of the tubular member, the distal portion, the intermediate portion, and the proximal portion being in fluid communication via a lumen extending inside the tubular member, the distal portion of the tubular member having a plurality of perforations, wherein the proximal portion is free of perforations, and the proximal end having an opening in fluid communication with the lumen and with the perforations, the distal end of the tubular member being closed; and

a catheter in fluid communication with the lumen of the tubular member, the catheter having a distal end and a proximal end, the distal end of the catheter being attached to the proximal end of the tubular member located relative to the hub longitudinally opposite the struts, the proximal end of the catheter residing outside the blood vessel;

injecting a fluid into the proximal end of the catheter.

15. The method of claim 14, wherein the fluid is a drug.

16. The method of claim 15, wherein the drug is an anti-coagulant.

17. The method of claim 16, wherein the anti-coagulant is heparin.

18. The method of claim 14, wherein the fluid is injected continuously over a period of time.

19. The method of claim 18, wherein the period of time is between two and six days.