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Methods for treating spinal cord injury

  • US 10,022,419 B2
  • Filed: 11/02/2015
  • Issued: 07/17/2018
  • Est. Priority Date: 10/21/2011
  • Status: Active Grant
First Claim
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1. A method for treating a spinal cord injury in a subject by promoting axon regeneration in a Central Nervous System (CNS) neuron, the method comprising:

  • exposing the CNS neuron of the subject to an effective amount of a necrostatin and an effective amount of an apoptosis inhibitor thereby to promote the regeneration of the axon of the CNS neuron;

    wherein the necrostatin is selected from the group consisting of;

    (i) a Nec-1 related compound of Formula I;

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