Anti-adherent alcohol-based composition

• US 10,028,899 B2
• Filed: 04/01/2015
• Issued: 07/24/2018
• Est. Priority Date: 07/31/2014
• Status: Active Grant

• Current Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Chaudhary, Vinod, Wenzel, Scott W., Engelbrecht, Kathleen C., Koenig, David W., Vanden Heuvel, Amy L., Bhatt, Divesh, Anunson, Paige N., Mundschau, Stacy A.
• Primary Examiner(s): HUI, SAN MING R
• Application Number:
  US15/500,671
• Publication Number:
  US 20170224596A1
• Time in Patent Office: 1,210 Days
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/73 Polysaccharides
• CPC Class Codes: A61K 8/731 Cellulose; Quaternized cellulose derivatives
• CPC Class Codes: A61K 8/8152 Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: C09D 101/28 Alkyl ethers
• CPC Class Codes: C09D 101/284 with hydroxylated hydrocarbon radicals
• CPC Class Codes: C09D 5/14 Paints containing biocides, e.g. fungicides, insecticides or pesticides C09D5/16 takes precedence
• CPC Class Codes: C09D 7/65 macromolecular C09D7/41-C09D7/48 take precedence
• CPC Class Codes: Y02A 50/30 Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The present disclosure is directed to alcohol-based anti-adherent compositions that do not adhere to or attract Gram-negative and Gram-positive bacteria once it is applied to a surface and dried. The composition may include as anti-adherent agents, hydrophilic film-formers such as cellulosics, gums, acrylates, nonionic polymers, and anionic polymers. Examples of anti-adherent agents include Hydroxypropyl methylcellulose, Cellulose gum, Acacia Senegal Gum; Polyacrylate Crosspolymer-11, VP/Dimethyl-aminoethylmethacrylate/Polycarbamyl Polyglycol Ester; Acrylates/Vinyl Neodecanoate Crosspolymer, hydroxypropyl methylcellulose, Hydroxypropylcellulose, Methylcellulose, Propylene Glycol Alginate, Polyacrylate Crosspolymer-6, VP/Polycarbamyl Polyglycol Ester, Acrylates/Steareth-20 Methacrylate Copolymer; Acrylates Copolymer, and any combination thereof. The anti-adherent may be applied to surfaces using a vehicle such as a wipe.

Claims

1. A anti-adherent composition for use on surfaces, the composition comprising:

62% to 72% (by weight of composition) of a short-chain alcohol; and

an anti-adherent agent selected from the group consisting of Acacia Senegal Gum;

Polyacrylate Crosspolymer-11;

VP/Dimethylaminoethylmethacrylate/Polycarbamyl Polyglycol Ester;

Acrylates/Vinyl Neodecanoate Crosspolymer;

Propylene Glycol Alginate;

Polyacrylate Crosspolymer-6;

VP/Polycarbamyl Polyglycol Ester; and

combinations thereof.

2. The composition of claim 1 wherein the anti-adherent agent comprises Polyacrylate Crosspolymer-11.

3. The composition of claim 1 wherein the anti-adherent agent comprises Polyacrylate Crosspolymer-11, and wherein the composition further includes Hydroxypropyl methylcellulose (HPMC), and wherein the weight/weight ratio of HPMC to Polyacrylate Crosspolymer-11 ranges from 10:

1 to 1;

10, respectively.

4. The composition of claim 1 wherein the anti-adherent agent is present in the amount of 0.01% to 20% by weight of the composition.

5. The composition of claim 1 wherein composition reduces the adherence of microbes on the surface by at least 0.5 LOG according to the High Throughput Anti-adherence Test Method or the Viable Count Anti-Adherence Test Method.

6. The composition of claim 1 wherein composition reduces the adherence of microbes on the surface by at least 1 LOG according to the High Throughput Anti-adherence Test Method or the Viable Count Anti-Adherence Test Method.

7. The composition of claim 1 further comprising a hydrophilic carrier.

8. A anti-adherent composition for use on surfaces, the composition comprising:

40% to 90% (by total weight of composition) of a short-chain alcohol;

0.01% to 20% (by total weight of composition) of an anti-adherent agent, wherein the anti-adherent agent comprises Polyacrylate Crosspolymer-11 and at least one agent selected from the group consisting of;

Hydroxypropyl methylcellulose, Cellulose gum, Acacia Senegal Gum;

VP/Dimethylaminoethylmethacrylate/Polycarbamyl Polyglycol Ester;

Acrylates/Vinyl Neodecanoate Crosspolymer;

hydroxypropyl methylcellulose;

Hydroxypropylcellulose;

Methylcellulose;

Propylene Glycol Alginate;

Polyacrylate Crosspolymer-6;

VP/Polycarbamyl Polyglycol Ester;

Acrylates/Steareth-20 Methacrylate Copolymer;

Acrylates Copolymer; and

combinations thereof; and

water;

wherein the composition reduces the adherence of E. coli and S. aureus on the surfaces by at least 0.5 LOG according to the High Throughput Anti-adherence Test Method or the Viable Count Anti-Adherence Test Method.

9. The composition of claim 8 further comprising a humectant selected from the group consisting of glycerin, glycerin derivatives, hyaluronic acid derivatives, betaine derivatives amino acids, amino acid derivatives, glycosaminoglycans, glycols, polyols, sugars, sugar alcohols, hydrogenated starch hydrolysates, hydroxy acids, hydroxy acid derivatives, salts of PCA, and combinations thereof.

10. The composition of claim 8 further comprising a humectant selected from the group consisting of honey, sorbitol, hyaluronic acid, sodium hyaluronate, betaine, lactic acid, citric acid, sodium citrate, glycolic acid, sodium glycolate, sodium lactate, urea, propylene glycol, butylene glycol, pentylene glycol, ethoxydiglycol, methyl gluceth-10, methyl gluceth-20, PEG-2, PEG-3, PEG-4, PEG-5, PEG-6, PEG-7, PEG-8, PEG-9, PEG 10, Propanediol, xylitol, maltitol, and a combination thereof.

11. The composition of claim 8 wherein the composition reduces the adherence of E. coli and S. aureus on the surfaces by at least 1 LOG according to the High Throughput Anti-adherence Test Method or the Viable Count Anti-Adherence Test Method.

12. The composition of claim 8 further comprising a foaming agent.

13. A wipe comprising:

a nonwoven substrate; and

an anti-adherent composition comprising 40% to 90% (by total weight of composition) of a short-chain alcohol;

0.01% to 20% (by total weight of composition) of an anti-adherent agent, wherein the anti-adherent agent comprises Polyacrylate Crosspolymer-11 and a modified cellulose; and

a hydrophilic carrier;

wherein the composition reduces the adherence of E. coli and S. aureus on the surfaces by at least 0.5 LOG according to the High Throughput Anti-adherence Test Method.

14. The wipe of claim 13 wherein the anti-adherent composition further comprises a humectant.

15. The wipe of claim 13 wherein the modified cellulose comprises Methylcellulose, Hydroxypropyl methylcellulose (HPMC), or a combination thereof.

16. The wipe of claim 13 wherein the anti-adherent agent is present in the amount of 0.1% to 10% (by total weight of the composition).

17. A anti-adherent composition for use on surfaces, the composition comprising:

40% to 90% (by weight of composition) of a short-chain alcohol; and

an anti-adherent agent comprising Polyacrylate Crosspolymer-11.

18. The composition of claim 17, wherein the composition further includes Hydroxypropyl methylcellulose (HPMC), and wherein the weight/weight ratio of HPMC to Polyacrylate Crosspolymer-11 ranges from 10:

1 to 1;

10, respectively.

19. The composition of claim 17, wherein the short-chain alcohol is present in the amount of 62%-72% by weight of the composition.