Lactate measuring device and method for training adjustment in sports

• US 10,034,626 B2
• Filed: 09/10/2014
• Issued: 07/31/2018
• Est. Priority Date: 01/28/2014
• Status: Active Grant

• Current Assignee: National Taipei University Of Technology, Richhealth Technology Corporation
• Original Assignee: Micro Nipple Technology Co., Ltd.
• Inventors: Huang, Juang-Tang
• Primary Examiner(s): JANG, CHRISTIAN YONGKYUN
• Application Number:
  US14/483,146
• Publication Number:
  US 20150208970A1
• Time in Patent Office: 1,420 Days
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/4866 Evaluating metabolism A61B5/083 takes precedence
• CPC Class Codes: A61B 5/685 Microneedles

Abstract

The invention relates to a method for training adjustment in sports. The method may measure lactate concentrations in the body of a person by a lactate measuring device comprising a transdermal microneedles sensor. The method for training adjustment in sports includes steps of: measuring a lactate concentration value in the body of a user by the transdermal microneedles sensor; comparing the lactate concentration value with a predetermined value; and informing the user to reduce exercise intensity if the lactate concentration value is higher than the predetermined value, otherwise informing the user to increase exercise intensity if the lactate concentration value is lower than the predetermined value. The invention also relates to a lactate measuring device.

Claims

1. A method for training adjustment in sports, with which a lactate measuring device comprising a continuous transdermal microneedles sensor is used to measure lactate concentration in a human body, the method including steps of:

measuring a lactate concentration value in the body of a user by the continuous transdermal microneedles sensor;

comparing the lactate concentration value with a predetermined value; and

informing the user to reduce exercise intensity if the lactate concentration value is higher than the predetermined value, and otherwise informing the user to increase exercise intensity if the lactate concentration value is lower than the predetermined value;

wherein the continuous transdermal microneedles sensor comprises;

a substrate;

a microneedle unit comprising at least a first microneedle set used as a working electrode and a second microneedle set used as a reference electrode, each of the microneedle sets comprising at least a microneedle, the first microneedle set comprising at least two sheets, each of the sheets having a through hole defined thereon and a barbule arranged at the peripheral of the through hole, the through hole on one sheet allowing the corresponding barbules of another sheet to pass and the barbules being disposed separately;

a signal processing unit arranged on the substrate and electrically connecting to the first microneedle set and the second microneedle set; and

a power supply unit providing working power to the transdermal microneedles sensor.

2. The method for training adjustment in sports in claim 1, wherein the first microneedle set comprises a first sheet and a second sheet stacked with the first sheet, the first sheet having at least one first through hole defined thereon, and a first barbule at peripheral of the first through hole, the second sheet having at least one second through hole defined thereon and a second barbule at peripheral of the second through hole, wherein the second barbule penetrates the first through hole to juxtapose the first barbule at corresponding location.

3. The method for training adjustment in sports in claim 1, wherein the first microneedle set comprises a first sheet, a second sheet and a third sheet stacked with each other, the first sheet having at least one first through hole defined thereon, and a first barbule at peripheral of the first through hole, the second sheet having at least one second through hole defined thereon and a second barbule at peripheral of the second through hole, the third sheet having at least one third through hole defined thereon and a third barbule at peripheral of the third through hole, wherein the second barbule and the third barbule penetrate the first through hole to juxtapose the first barbule, and tips of the barbules are in triangular arrangement.

4. The method for training adjustment in sports in claim 1, wherein the first microneedle set comprises a first sheet, a second sheet, a third sheet and a fourth sheet stacked with each other, the first sheet having at least one first through hole defined thereon, and a first barbule at peripheral of the first through hole, the second sheet having at least one second through hole defined thereon and a second barbule at peripheral of the second through hole, the third sheet having at least one third through hole defined thereon and a third barbule at peripheral of the third through hole, the fourth sheet having at least one fourth through hole defined thereon and a fourth barbule at peripheral of the fourth through hole, wherein the second barbule, the third barbule and the fourth barbule penetrate the first through hole to juxtapose the first barbule, and tips of the barbules are in rectangular arrangement.

5. The method for training adjustment in sports in claim 1, wherein the microneedles of first microneedle set and the second microneedle set are formed by punching or etching.

6. The method for training adjustment in sports in claim 1, wherein each the barbules has lactate sensing enzyme coated on inner surface thereof.

7. The method for training adjustment in sports in claim 1, wherein each the barbules has anti-irritation medicine coated on outer surface thereof.

8. The method for training adjustment in sports in claim 1, wherein the continuous transdermal microneedles sensor further comprises a test strip arranged between the first microneedle set and the substrate, the test strip comprises a conductive layer and a plurality of test areas on the conductive layer, the test areas are coated with sensing polymer and aligned with the through holes of the first microneedle set.

9. The method for training adjustment in sports in claim 6, further comprising a protection layer on the lactate sensing enzyme.

10. The method for training adjustment in sports in claim 7, further comprising a protection layer on the anti-irritation medicine.

11. The method for training adjustment in sports in claim 1, wherein the material of the barbules is selected from the group consisting of stainless steel, nickel, nickel alloy, titanium, titanium alloy, carbon nanotube, and silicon, the surface of the barbules is coated with biologically compatible metal.

12. The method for training adjustment in sports in claim 1, wherein the material of the barbules is resin, the surface of the barbules is coated with biologically compatible metal.

13. The method for training adjustment in sports in claim 1, the predetermined value is lactate threshold (LT), anaerobic threshold, maximal lactate steady state (MLSS) or onset of blood lactate accumulation (OBLA).

14. The method for training adjustment in sports in claim 1, the predetermined value is individual anaerobic threshold (IAT) of a user.

15. A lactate measuring device, comprising:

a substrate;

a microneedle unit comprising at least a first microneedle set used as a working electrode and a second microneedle set used as a reference electrode, each of the microneedle sets comprising at least a microneedle, the first microneedle set comprising at least two sheets, each of the sheets having a through hole defined thereon and a barbule arranged at the peripheral of the through hole, the through hole on one sheet allowing the corresponding barbules of another sheet to pass and the barbules being disposed separately;

a signal processing unit arranged on the substrate and electrically connecting to the first microneedle set and the second microneedle set;

a comparator for comparing a lactate concentration value from the signal processing unit and a predetermined value; and

a power supply unit providing working power to the transdermal microneedles sensor.

16. The lactate measuring device in claim 15, wherein the microneedles of first microneedle set and the second microneedle set are formed by punching or etching.

17. The lactate measuring device in claim 15, wherein each the barbules has lactate sensing enzyme coated on inner surface thereof.

18. The lactate measuring device in claim 15, wherein each the barbules has anti-irritation medicine coated on outer surface thereof.

19. The lactate measuring device in claim 15, further comprising a test strip arranged between the first microneedle set and the substrate, the test strip comprises a conductive layer and a plurality of test areas on the conductive layer, the test areas are coated with sensing polymer and aligned with the through holes of the first microneedle set.