Temporal echogenic markers

• US 10,034,655 B2
• Filed: 02/03/2014
• Issued: 07/31/2018
• Est. Priority Date: 02/05/2013
• Status: Active Grant

• Current Assignee: Muffin Incorporated
• Original Assignee: Muffin Incorporated
• Inventors: McKinnis, Peter S., Zhou, Yun, Fearnot, Neal E.
• Primary Examiner(s): Chen, Tse
• Assistant Examiner(s): Sunwoo, Nate S
• Application Number:
  US14/170,705
• Publication Number:
  US 20140221820A1
• Time in Patent Office: 1,639 Days
• Field of Search: None
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 8/0841 for locating instruments
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: A61B 8/488 involving Doppler signals
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

Devices and methods for enhancing observability under ultrasound imaging of medical devices include temporal markers which are dynamic, producing a variable ultrasound image over time. Included are rotating markers which produce a Doppler shift visible through ultrasound imaging in a Doppler mode and which enhance visibility of the marker. Other devices and methods include alternating streams of fluid contrast agents and saline as well as destroying a fluid contrast agent stream with a high intensity ultrasound pulse.

Claims

1. A medical device for use with an ultrasound imaging system configured to process ultrasound signals and display images in ultrasound procedures comprising:

a marker which is capable of reflecting ultrasound waves;

wherein the marker is movable about an axis of rotation between a first position and a second position;

wherein the marker further includes a first portion configured to reflect a first ultrasound wave back to an ultrasound wave source and a second portion configured to reflect a second ultrasound wave back to the ultrasound wave source and wherein said first portion is offset to one side of said axis of rotation and said second portion is offset to the other side of said axis of rotation;

wherein the marker further includes echogenic enhancements located on surfaces of the marker, whereby when an ultrasound signal is applied to the marker the echogenic enhancements cause a scattering of the ultrasound waves; and

,

wherein when said marker moves between said first position and said second position, said first portion of the marker moves towards the ultrasound wave source, while said second portion of the marker moves away from the ultrasound wave source, whereby when the medical device is placed within a body and viewed on the ultrasound imaging system during ultrasound imaging procedures, the first and second portions of the marker concurrently reflect a portion of the ultrasound waves back to the ultrasound wave source, and whereby the ultrasound waves reflected from the first portion have a higher frequency than the ultrasound waves reflected from the second portion.

2. The medical device of claim 1, wherein said marker is rotatable about the axis of rotation at a first rotation rate;

and

wherein when positioned within a body and when rotating at the first rotation rate the marker produces a Doppler shift which is observable through ultrasound imaging procedures when the marker is subjected to ultrasound waves.

3. The medical device of claim 2, wherein the medical device is configured to be implanted within a human body.

4. The medical device of claim 2, further comprising a battery and an ultrasound sensor, wherein rotation of the marker is powered by the battery, wherein the medical device is switchable between an active state and an inactive state, wherein when in the active state the marker rotates and when in the inactive state the marker does not rotate, and wherein subjecting the ultrasound sensor to ultrasound waves changes the medical device from the inactive state to the active state.

5. The medical device of claim 2, wherein rotation of said marker causes the first portion of the marker to appear as a first color on the ultrasound imaging system, and causes the second portion of the marker to appear as a second color on the ultrasound imaging system.

6. The medical device of claim 2, wherein the direction of rotation of the marker is periodically changeable over time.

7. The medical device of claim 1, wherein when the marker is placed within a body and viewed on an ultrasound image during ultrasound imaging procedures, sequential movements of the marker between the first position and the second position cause a blink on the ultrasound image.

8. The medical device of claim 1, wherein the marker further comprises echogenic enhancements located on surfaces of the marker, whereby when ultrasound waves are applied to the marker the echogenic enhancements cause a scattering of the ultrasound waves.

9. The medical device of claim 8, wherein said echogenic enhancements comprise concave depressions located on the surface of the marker.

10. The medical device of claim 1, further comprising a battery and an ultrasound sensor, wherein rotation of the marker is powered by the battery, wherein the medical device is switchable between an active state and an inactive state, wherein when in the active state the marker rotates and when in the inactive state the marker does not rotate, and wherein subjecting the ultrasound sensor to ultrasound waves changes the medical device from the inactive state to the active state.

11. The medical device of claim 1, wherein the marker is a flat, planar shaped object rotatably fixed to a shaft having a shaft axis which is coaxial with the rotation axis.

12. The medical device of claim 1, wherein the marker is a helix shaped object fixed to a shaft having a shaft axis which is coaxial with the rotation axis.

13. The medical device of claim 1, wherein the medical device is configured to be implanted within a human body.

14. The medical device of claim 1, wherein the marker is rotatable about the axis of rotation at a variable rotation rate.

15. The medical device of claim 1, wherein the marker further comprises ultrasound absorbers located on surfaces of the marker, and wherein the ultrasound absorbers cause said marker to become more echolucent at the surfaces where the ultrasound absorbers are present.

16. A medical device for use with ultrasound procedures comprising:

a marker which is capable of reflecting ultrasound waves;

wherein the marker is movable about an axis of rotation between a first position and a second position;

wherein the marker further includes a first portion configured to reflect ultrasound waves back to an ultrasound wave source and a second portion configured to reflect ultrasound waves back to the ultrasound wave source and wherein said first portion is offset to one side of said axis of rotation and said second portion is offset to the other side of said axis of rotation;

wherein the marker further includes echogenic enhancements located on surfaces of the marker, whereby when an ultrasound signal is applied to the marker the echogenic enhancements cause a scattering of the ultrasound waves; and

,

wherein when said marker moves between said first position and said second position, said first portion of the marker moves towards the ultrasound wave source, while said second portion of the marker moves away from the ultrasound wave source, whereby when the medical device is placed within a body and viewed on an ultrasound image during ultrasound imaging procedures, the first and second portions of the marker concurrently reflect a portion of the ultrasound waves back to the ultrasound wave source, and whereby the ultrasound waves reflected from the first portion have a higher frequency than the ultrasound waves reflected from the second portion; and

,

wherein the medical device includes a converter which includes a piezoelectric element excitable by ultrasound waves, wherein the converter converts ultrasound wave energy into rotational energy, whereby when the medical device is placed within a body and viewed on an ultrasound image during ultrasound imaging procedures, application of ultrasound waves to the medical device causes the marker to rotate about the axis of rotation.

17. The medical device of claim 16, wherein said marker is rotatable about an axis at a first rotation rate;

and

wherein when positioned within a body and when rotating at the first rotation rate the marker produces a Doppler shift which is observable through ultrasound imaging procedures when the marker is subjected to ultrasound waves.