Catheter with irrigated tip electrode with porous substrate and high density surface micro-electrodes

• US 10,034,707 B2
• Filed: 12/30/2014
• Issued: 07/31/2018
• Est. Priority Date: 12/30/2014
• Status: Active Grant

• Current Assignee: Biosense Webster Israel Ltd. (Johnson & Johnson)
• Original Assignee: Biosense Webster Israel Ltd. (Johnson & Johnson)
• Inventors: Papaioannou, Athanassios, Beeckler, Christopher Thomas, Govari, Assaf
• Primary Examiner(s): Cohen, Lee S
• Application Number:
  US14/586,907
• Publication Number:
  US 20160184008A1
• Time in Patent Office: 1,309 Days
• Field of Search: 600374, 600381, 606 41
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00065 porous
• CPC Class Codes: A61B 2018/00148 with metal
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe
• CPC Class Codes: A61B 2018/1472 for use with liquid electrolyte, e.g. virtual electrodes
• CPC Class Codes: A61B 2018/1497 Electrodes covering only part of the probe circumference
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6852 Catheters

Abstract

A catheter has a multifunctional “virtual” tip electrode with a porous substrate and a multitude of surface microelectrodes. The surface microelectrodes are in close proximity to each other and in a variety of configurations so as to sense tissue for highly localized intracardiac signal detection, and high density local electrograms and mapping. The porous substrate allows for flow of conductive fluid for ablating tissue. The surface microelectrodes can be formed via a metallization process that allows for any shape or size and close proximity, and the fluid “weeping” from the porous substrate provides more uniform irrigation in the form of a thin layer of saline. The delivery of RF power to the catheter tip is based on the principle of “virtual electrode,” where the conductive saline flowing through the porous tip acts as the electrical connection between the tip electrode and the heart surface. The substrate and the surface electrodes are constructed of MRI compatible materials so that the physician can conduct lesion assessment in real time during an ablation procedure. The surface electrodes include noble metals, including, for example, platinum, gold and combinations thereof.

Claims

1. A catheter comprising:

an elongated catheter body;

a distal electrode member distal of the catheter body and having a porous substrate and a plurality of surface electrodes on portions of an outer surface of the porous substrate, the porous substrate having an interior chamber adapted to receive conductive fluid;

a plurality of electrode lead wires, each having a distal end connected on an outer surface of the porous substrate to a respective one of the surface electrodes and a proximal end extending through the catheter body, at least one of the plurality of electrode lead wires having its distal end connected to a first one of the plurality of surface electrodes and a portion extending underneath and insulated from a second one of the plurality of surface electrodes; and

a chamber lead wire having a distal portion extending into the interior chamber, the chamber lead wire adapted to electrify the conductive fluid in the interior chamber,

wherein the porous substrate is adapted to pass the conductive fluid from the interior chamber to the outer surface of the porous substrate.

2. The catheter of claim 1, wherein the porous substrate comprises an MRI-compatible material.

3. The catheter of claim 1, wherein the surface electrodes comprise an MRI-compatible material.

4. The catheter of claim 1, wherein the porous substrate comprises at least one material from the group consisting of ceramic material, polyethylene and polytetrafluoroethylene.

5. The catheter of claim 1, further comprising an intermediate deflection section between the catheter body and the distal electrode member.

6. The catheter of claim 1, further comprising an irrigation tubing extending through the catheter body and adapted to deliver the conductive fluid to the interior chamber.

7. The catheter of claim 1, wherein each of the surface electrodes has a surface area ranging between 0.2mm² and 2.0 mm².

8. The catheter of claim 1, wherein the distal portion of the chamber lead wire extending in the interior chamber is nonlinear.

9. The catheter of claim 1, wherein the plurality of surface electrodes ranges between about one and twenty.

10. The catheter of claim 1, wherein each of the surface electrodes of the plurality of surface electrodes is shaped with a protrusion configuration.

11. A catheter comprising:

an elongated catheter body;

a distal electrode member distal the catheter body and having a porous substrate and a plurality of surface electrodes, the porous substrate having at least one exposed surface area spanning between at least a pair of the surface electrodes, the porous substrate having an interior chamber adapted to receive conductive fluid;

a plurality of electrode lead wires, each having a distal end connected on an outer surface of the porous substrate to a respective one of the surface electrodes and a proximal end extending through the catheter body, at least one of the plurality of electrode lead wires having its distal end connected to a first one of the plurality of surface electrodes and a portion extending underneath and insulated from a second one of the plurality of surface electrodes; and

a chamber lead wire having a distal portion extending into the interior chamber, the chamber lead wire adapted to electrify the conductive fluid in the interior chamber,

wherein the porous substrate is adapted to pass the conductive fluid from the interior chamber to the at least one exposed surface area.

12. The catheter of claim 11, wherein the porous substrate comprises an MRI-compatible material.

13. The catheter of claim 12, wherein the porous substrate comprises a ceramic material.

14. The catheter of claim 11, wherein the surface electrodes comprise an MRI-compatible material.

15. The catheter of claim 11, further comprising an intermediate deflection section between the catheter body and the distal electrode member.

16. The catheter of claim 11, further comprising an irrigation tubing extending through the catheter body and adapted to deliver fluid to the interior chamber.

17. The catheter of claim 11, wherein the distal portion of the chamber lead wire extending in the interior chamber is coiled.

18. The catheter of claim 11, wherein the plurality of surface electrodes ranges between about six and twelve.

19. The catheter of claim 11, further comprising a plug member at a proximal end of the porous substrate.

20. A catheter comprising:

an elongated catheter body;

an intermediate deflection section distal of the catheter body;

a distal electrode member distal of the intermediate deflection section and having a porous substrate and a plurality of surface electrodes, the porous substrate having at least one exposed surface area spanning between at least a pair of the surface electrodes, the porous substrate having an interior chamber adapted to receive conductive fluid;

a plurality of electrode lead wires, each having a distal end connected on an outer surface of the porous substrate to a respective one of the surface electrodes and a proximal end extending through the catheter body, at least one of the plurality of electrode lead wires having its distal end connected to a first one of the plurality of surface electrodes and a portion extending underneath and insulated from a second one of the plurality of surface electrodes;

an irrigation tubing extending through the catheter body and the intermediate section and adapted to pass the conductive fluid into the interior chamber;

a chamber lead wire having a distal portion extending into the interior chamber, the chamber lead wire adapted to electrify the conductive fluid in the interior chamber,

wherein the porous substrate is adapted to pass the conductive fluid from the interior chamber to the at least one exposed surface area.