Glass articles with low-friction coatings

• US 10,034,816 B2
• Filed: 12/09/2016
• Issued: 07/31/2018
• Est. Priority Date: 02/28/2012
• Status: Active Grant

• Current Assignee: Corning Incorporated
• Original Assignee: Corning Incorporated
• Inventors: Fadeev, Andrei Gennadyevich, Chang, Theresa, Bookbinder, Dana Craig, Pal, Santona, Saha, Chandan Kumar, DeMartino, Steven Edward, Timmons, Christopher Lee, Peanasky, John Stephen
• Primary Examiner(s): HIGGINS, GERARD T
• Application Number:
  US15/374,338
• Publication Number:
  US 20170087058A1
• Time in Patent Office: 599 Days
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: B65D 23/0821 consisting mainly of polymeric materials B65D23/0828 takes precedence
• CPC Class Codes: C03C 17/005 Coating the outside
• CPC Class Codes: C03C 17/30 with silicon-containing compounds
• CPC Class Codes: C03C 17/32 with synthetic or natural resins C03C17/30 takes precedence
• CPC Class Codes: C03C 17/42 at least one coating of an organic material and at least one non-metal coating
• CPC Class Codes: C03C 21/002 to perform ion-exchange between alkali ions C03C21/005 takes precedence
• CPC Class Codes: C03C 2217/78 Coatings specially designed to be durable, e.g. scratch-resistant
• CPC Class Codes: C03C 2218/111 by dipping, immersion
• CPC Class Codes: Y10T 428/1321 Polymer or resin containing [i.e., natural or synthetic]
• CPC Class Codes: Y10T 428/24926 including ceramic, glass, porcelain or quartz layer
• CPC Class Codes: Y10T 428/24942 including components having same physical characteristic in differing degree
• CPC Class Codes: Y10T 428/265 1 mil or less
• CPC Class Codes: Y10T 428/31612 As silicone, silane or siloxane
• CPC Class Codes: Y10T 428/31623 Next to polyamide or polyimide

Abstract

A pharmaceutical package may include a glass body enclosing an inner volume and having an exterior surface. The glass body may be formed from a borosilicate glass that meets the Type 1 criteria according to USP <660>or an alkali aluminosilicate glass having a Class HGA 1 hydrolytic resistance when tested according to the ISO 720-1985 testing standard. A coupling agent layer having a first thickness less than or equal to 100 nm may be disposed on the exterior surface of the glass body. A polymer layer having a second thickness of less than 50 nm may be positioned over the coupling agent layer. The exterior surface of the glass body with the coupling agent layer and the polymer layer may have a coefficient of friction less than or equal to 0.7.

Claims

1. A pharmaceutical package comprising:

a glass body enclosing an inner volume and having an exterior surface, wherein the glass body is formed from a borosilicate glass that meets the Type 1 criteria according to USP <

660>

; and

a low-friction coating on the exterior surface of the glass body, the low-friction coating comprising;

a coupling agent layer having a first thickness less than or equal to 100 nm disposed on the exterior surface of the glass body; and

a polymer layer having a second thickness of less than 50 nm positioned over the coupling agent layer, wherein the exterior surface of the glass body with the low-friction coating has a coefficient of friction less than or equal to 0.7.

2. The pharmaceutical package of claim 1, wherein the first thickness is less than 90 nm.

3. The pharmaceutical package of claim 1, wherein the first thickness is less than 80 nm.

4. The pharmaceutical package of claim 1, wherein the first thickness is less than 70 nm.

5. The pharmaceutical package of claim 4, wherein the second thickness is less than 25 nm.

6. The pharmaceutical package of claim 1, wherein the first thickness is less than 60 nm.

7. The pharmaceutical package of claim 1, wherein the second thickness is less than 25 nm.

8. The pharmaceutical package of claim 1 wherein:

the portion of the exterior surface of the glass body with the low-friction coating has a coefficient of friction of less than or equal to 0.6 relative to a like-coated glass pharmaceutical package; and

a light transmission through the pharmaceutical package is greater than or equal to about 55% of a light transmission through an uncoated pharmaceutical package for each wavelength from about 400 nm to about 700 nm.

9. The pharmaceutical package as recited in claim 1, wherein a coefficient of friction of the portion of the exterior surface of the glass body with the low-friction coating is less than or equal to 0.6 after undergoing a depyrogenation cycle at a temperature of from 250°

C. to 400°

C. for a time period of from 30 seconds to 72 hours.

10. The pharmaceutical package of claim 9, wherein the depyrogenation cycle comprises heating the pharmaceutical package to a temperature of 250°

C. for 30 minutes.

11. The pharmaceutical package of claim 9, wherein the depyrogenation cycle comprises heating the pharmaceutical package to a temperature of 300°

C. for 30 minutes.

12. The pharmaceutical package of claim 9, wherein the depyrogenation cycle comprises heating the pharmaceutical package to a temperature of from about 260°

C. to about 400°

C. for a time period of 30 minutes.

13. The pharmaceutical package of claim 1, wherein the polymer layer comprises a polyimide.

14. The pharmaceutical package of claim 1, wherein the coupling agent layer comprises an inorganic material.

15. The pharmaceutical package of claim 1, wherein the coupling agent layer comprises at least one of titanates, zirconates, tin, titanium, tin oxide, or titanium oxide.

16. The pharmaceutical package of claim 1, wherein the coupling agent layer comprises a silane comprising an amine moiety.

17. The pharmaceutical package of claim 1, wherein:

the portion of the exterior surface of the glass body with the low-friction coating has a coefficient of friction of less than or equal to 0.6, wherein the coefficient of friction is a maximum coefficient of friction measured relative to a second pharmaceutical package in a vial-on-vial testing jig under a normal load of 30 N, the second pharmaceutical package formed from the same glass composition and comprising the coupling agent layer and the polymer layer on at least a portion of a second exterior outer surface of the second pharmaceutical package and subjected to the same environmental conditions prior to measurement of the coefficient of friction; and

the portion of the exterior surface of the glass body with the low-friction coating contains less than 6 glass checks per 5 mm length when abraded along a length of about 20 mm with the second pharmaceutical package in the vial-on-vial testing jig under the normal load of 30 N after exposure of the pharmaceutical package and the second pharmaceutical package to a temperature of at least about 260°

C. for 30 minutes.

18. The pharmaceutical package of claim 1, wherein a coefficient of friction of the portion of the glass body with the low friction coating is at least 20% less than a coefficient of friction of a surface of an uncoated pharmaceutical package formed from the same glass composition.

32. The pharmaceutical package as recited in claim 1, wherein a coefficient of friction of the portion of the exterior surface of the glass body with the low-friction coating is less than or equal to 0.6 after undergoing a depyrogenation cycle at a temperature of from 250°

C. to 400°

C. for a time period of from 30 seconds to 72 hours.

33. The pharmaceutical package of claim 32, wherein the depyrogenation cycle comprises heating the pharmaceutical package to a temperature of 250°

C. for 30 minutes.

34. The pharmaceutical package of claim 32, wherein the depyrogenation cycle comprises heating the pharmaceutical package to a temperature of 300°

C. for 30 minutes.

35. The pharmaceutical package of claim 32, wherein the depyrogenation cycle comprises heating the pharmaceutical package to a temperature of from about 260°

C. to about 400°

C. for a time period of 30 minutes.

19. A coated glass pharmaceutical package comprising:

a glass body having an interior surface and an exterior surface and a wall extending therebetween, wherein the glass body is formed from a borosilicate glass that meets the Type 1 criteria according to USP <

660>

; and

a low-friction coating on the exterior surface of the glass body, the low-friction coating comprising;

a coupling agent layer having a first thickness of less than 100 nm; and

a polymer layer having a second thickness of less than 50 nm positioned over the coupling agent layer, wherein the exterior surface of the glass body with the low-friction coating has a coefficient of friction less than or equal to 0.7.

20. A pharmaceutical package comprising:

a glass body having a hollow interior and an exterior surface, wherein the glass body is formed from a borosilicate glass that meets the Type 1 criteria according to USP <

660>

; and

a low-friction coating on the exterior surface of the glass body, the low-friction coating comprising;

a coupling agent layer having a first thickness; and

a polymer layer positioned over the coupling agent layer and having a second thickness;

wherein the first thickness is less than or equal to 100 nm, the second thickness is less than or equal to 100 nm, and the exterior surface of the glass body with the low-friction coating has a coefficient of friction less than or equal to 0.7.

21. The pharmaceutical package of claim 20, wherein the first thickness is less than 90 nm.

22. The pharmaceutical package of claim 20, wherein the second thickness is less than 50 nm.

23. The pharmaceutical package of claim 20, wherein the portion of the exterior surface of the glass body with the low-friction coating has a coefficient of friction of less than or equal to 0.6 relative to a like-coated glass pharmaceutical package.

24. A pharmaceutical package comprising:

a glass body enclosing an inner volume and having an exterior surface, wherein the glass body is formed is formed from an alkali aluminosilicate glass having a Class HGA 1 hydrolytic resistance when tested according to the ISO 720-1985 testing standard; and

a low-friction coating on the exterior surface of the glass body, the low-friction coating comprising;

a coupling agent layer having a first thickness less than or equal to 100 nm; and

a polymer layer having a second thickness of less than 50 nm positioned over the coupling agent layer, wherein the exterior surface of the glass body with the low-friction coating has a coefficient of friction less than or equal to 0.7.

25. The pharmaceutical package of claim 24, wherein the first thickness is less than 90 nm.

26. The pharmaceutical package of claim 24, wherein the first thickness is less than 80 nm.

27. The pharmaceutical package of claim 24, wherein the first thickness is less than 70 nm.

28. The pharmaceutical package of claim 27, wherein the second thickness is less than 25 nm.

29. The pharmaceutical package of claim 24, wherein the first thickness is less than 60 nm.

30. The pharmaceutical package of claim 24, wherein the second thickness is less than 25 nm.

31. The pharmaceutical package of claim 24 wherein:

the portion of the exterior surface of the glass body with the low-friction coating has a coefficient of friction of less than or equal to 0.6 relative to a like-coated glass pharmaceutical package; and

a light transmission through the pharmaceutical package is greater than or equal to about 55% of a light transmission through an uncoated pharmaceutical package for each wavelength from about 400 nm to about 700 nm.

36. The pharmaceutical package of claim 24, wherein the polymer layer comprises a polyimide.

37. The pharmaceutical package of claim 24, wherein the coupling agent layer comprises an inorganic material.

38. The pharmaceutical package of claim 24, wherein the coupling agent layer comprises at least one of titanates, zirconates, tin, titanium, tin oxide, or titanium oxide.

39. The pharmaceutical package of claim 24, wherein the coupling agent layer comprises a silane comprising an amine moiety.

40. The pharmaceutical package of claim 24, wherein:

the portion of the exterior surface of the glass body with the low-friction coating has a coefficient of friction of less than or equal to 0.6, wherein the coefficient of friction is a maximum coefficient of friction measured relative to a second pharmaceutical package in a vial-on-vial testing jig under a normal load of 30 N, the second pharmaceutical package formed from the same glass composition and comprising the coupling agent layer and the polymer layer on at least a portion of a second exterior outer surface of the second pharmaceutical package and subjected to the same environmental conditions prior to measurement of the coefficient of friction; and

the portion of the exterior surface of the glass body with the low-friction coating contains less than 6 glass checks per 5 mm length when abraded along a length of about 20 mm with the second pharmaceutical package in the vial-on-vial testing jig under the normal load of 30 N after exposure of the pharmaceutical package and the second pharmaceutical package to a temperature of at least about 260°

C. for 30 minutes.

41. The pharmaceutical package of claim 24, wherein a coefficient of friction of the portion of the glass body with the low friction coating is at least 20% less than a coefficient of friction of a surface of an uncoated pharmaceutical package formed from the same glass composition.

42. A coated glass pharmaceutical package comprising:

a glass body having an interior surface and an exterior surface and a wall extending therebetween, wherein the glass body is formed is formed from an alkali aluminosilicate glass having a Class HGA 1 hydrolytic resistance when tested according to the ISO 720-1985 testing standard; and

a low-friction coating on the exterior surface of the glass body, the low-friction coating comprising;

a coupling agent layer having a first thickness of less than 100 nm; and

a polymer layer having a second thickness of less than 50 nm positioned over the coupling agent layer, wherein the exterior surface of the glass body with the low-friction coating has a coefficient of friction less than or equal to 0.7.

43. A pharmaceutical package comprising:

a glass body having a hollow interior and an exterior surface, wherein the glass body is formed is formed from an alkali aluminosilicate glass having a Class HGA 1 hydrolytic resistance when tested according to the ISO 720-1985 testing standard; and

a low-friction coating on the exterior surface of the glass body, the low-friction coating comprising;

a coupling agent layer having a first thickness; and

a polymer layer positioned over the coupling agent layer and having a second thickness, wherein the first thickness is less than or equal to 100 nm, the second thickness is less than or equal to 100 nm, and the exterior surface of the glass body with the low-friction coating has a coefficient of friction less than or equal to 0.7.

44. The pharmaceutical package of claim 43, wherein the first thickness is less than 90 nm.

45. The pharmaceutical package of claim 43, wherein the second thickness is less than 50 nm.