Spindle for a drug delivery device

• US 10,034,982 B2
• Filed: 05/27/2010
• Issued: 07/31/2018
• Est. Priority Date: 06/01/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Plumptre, David Aubrey
• Primary Examiner(s): Price, Nathan R
• Assistant Examiner(s): Bui, Anh
• Application Number:
  US12/788,742
• Publication Number:
  US 20100331790A1
• Time in Patent Office: 2,987 Days
• Field of Search: 604134, 604135, 604155, 604207-211
• CPC Class Codes: A61M 2005/2407 from the rear
• CPC Class Codes: A61M 2005/2488 via rotation, e.g. threads or bayonet
• CPC Class Codes: A61M 2005/2492 via snap connection
• CPC Class Codes: A61M 2005/3152 including gearings to multiply or attenuate the piston displacing force
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31543 piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31558 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: Y10T 74/19721 Thread geometry
• CPC Class Codes: Y10T 74/19953 Worm and helical

Abstract

A spindle for driving a bung of a cartridge. The spindle includes a generally circular shaft having an outer surface. The generally circular shaft extends from a distal end to a proximal end of said circular shaft. A first helical groove is provided along a first portion of the outer surface. The first helical groove having a first pitch. A second helical groove provided along a second portion of the outer surface of the generally circular shaft. The second helical groove overlapping the first helical groove. The second helical groove having a second pitch.

Claims

1. A dose setting mechanism for use with a drug delivery device, said dose setting mechanism comprising:

a housing insert comprising a helical groove form;

a spindle for driving a bung of a cartridge, said spindle comprising;

a generally circular shaft having an outer surface;

a first helical groove provided along a first portion of said outer surface of said generally circular shaft, said first helical groove having a first pitch; and

a second helical groove provided along a second portion of said outer surface of said generally circular shaft, said second helical groove overlapping said first helical groove, said second helical groove having a second pitch, and said second helical groove engaging the helical groove form of the housing insert; and

a driver for driving said spindle, said driver comprising a helical groove form that engages said first helical groove provided along said first portion of said outer surface of said generally circular shaft of said spindle,

wherein a longitudinal axial movement of the driver causes the spindle to rotate, and

wherein the driver is prevented from rotating with respect to a drug delivery device housing during dispensing a dose.

2. The invention of claim 1 wherein said first helical groove comprises said first pitch of a first hand;

and said second helical groove comprising said second pitch of an opposite hand to said first hand of said first helical groove.

3. The invention of claim 1 wherein said first pitch of said first helical groove is equivalent to said second pitch of said second helical groove.

4. The invention of claim 1 wherein said second helical groove provided along said second portion of said outer surface of said generally circular shaft overlaps substantially all of said first helical groove.

5. The invention of claim 1 wherein said first helical groove provided along said outer surface of said generally circular shaft comprises a first helical female groove.

6. The invention of claim 1 wherein said second helical groove provided along said outer surface of said generally circular shaft and overlapping at least a portion of said first helical groove comprises a second helical female groove.

7. The invention of claim 1 wherein said helical groove form of the driver comprises a helical groove of less than one turn.

8. The invention of claim 1 wherein said first helical groove extends along said outer surface of said generally circular shaft from about said distal end of said spindle to about said proximal end of said spindle.

9. The invention of claim 1 wherein said second helical groove extends along said outer surface of said generally circular shaft from about said distal end of said spindle to about said proximal end of said spindle.

10. The invention of claim 1 wherein said helical groove form of said housing insert comprises a partial groove form.

11. The invention of claim 1 wherein said helical groove form of said housing insert comprises a less than one complete turn of said groove.

12. The invention of claim 1 wherein said cartridge comprises a removable cartridge of a drug delivery device.

13. The invention of claim 1 wherein said cartridge comprises a non-removable cartridge of a drug delivery device.

14. The invention of claim 1 wherein said first pitch of said first helical groove provided along said first portion of said outer surface has a first diameter and said second pitch of said second helical groove provided along said second portion of said outer surface has a second diameter.

15. The invention of claim 14 wherein said first diameter is generally equal to said second diameter.

16. The invention of claim 1, further comprising:

a rotating sleeve in rotatable engagement with respect to said drug delivery device housing;

wherein the driver is releasably coupled to said rotating sleeve such that when a user sets a dose by rotating said rotating sleeve, said driver also rotates.

17. The invention of claim 16 where said dose setting mechanism comprises a resettable dose setting mechanism.

18. The invention of claim 16 wherein said driver comprises a first component and a second component, said first and said second component being operatively coupled together so that they rotate together when said user sets said dose.

19. The invention of claim 16 wherein said dose setting mechanism comprises a non-resettable dose setting mechanism.

20. The invention of claim 17 wherein when said user resets said dose setting mechanism, a first component of said driver is decoupled from a second component of said driver and said first component can rotate back to an original position.

21. The invention of claim 20 wherein when said user resets said dose setting mechanism and said first component rotates back to said original position, a dose limiting device returns to an initial position.

22. The invention of claim 20 further comprising a cartridge holder releasably coupled to said dose setting mechanism.

23. The invention of claim 20 further comprising a cartridge holder releasably coupled to said dose setting mechanism by way of a bayonet coupling.

24. The invention of claim 20 further comprising a cartridge holder comprising a removable cartridge.