Systems and methods for drug delivery

• US 10,035,010 B1
• Filed: 09/28/2017
• Issued: 07/31/2018
• Est. Priority Date: 09/28/2017
• Status: Active Grant

• Current Assignee: Carydean Enterprises LLC
• Original Assignee: Carydean Enterprises LLC
• Inventors: Wagstaff, Dean Henry
• Primary Examiner(s): Vu, Quynh-Nhu H
• Application Number:
  US15/718,017
• Time in Patent Office: 306 Days
• CPC Class Codes: A61B 5/00 Measuring for diagnostic purposes radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00; Identification of persons
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/681 Wristwatch-type devices
• CPC Class Codes: A61M 2037/0007 having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
• CPC Class Codes: A61M 2205/0211 Ceramics
• CPC Class Codes: A61M 2205/0244 Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 35/10 Wearable devices, e.g. garments, glasses or masks
• CPC Class Codes: A61M 37/0092 using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis

Abstract

A wearable device for monitoring the body parameters of an individual and for delivering a drug and/or therapeutic agent. The device comprises a processing unit and a drug delivery unit. The processing unit comprises a sensor to determine body parameters of a user; a reservoir to store the drug; a processor to receive signals indicative of the body parameters from the sensor and determine a quantity of the drug to be delivered from the reservoir based on the body parameters; and a signal generator to generate electrical signals based on control instructions received from the processor. The drug delivery unit comprises a chamber to receive the determined quantity of the drug from the reservoir and a transducer connected to the chamber, wherein the transducer transdermally delivers the drug from the chamber to skin based on an electrical signal received from the signal generator.

Claims

1. A wearable device for delivering a drug, the wearable device comprising:

a processing unit comprising;

a sensor configured to determine a body parameter of a user;

a reservoir to store the drug;

a processor communicably coupled to the sensor, wherein the processor receives a signal indicative of the body parameter from the sensor, and wherein the processor determines a quantity of the drug to be delivered from the reservoir based on the body parameter; and

a signal generator to generate electrical signals based on control instructions received from the processor; and

a drug delivery unit connected to the processing unit, the drug delivery unit comprising;

a chamber to receive the determined quantity of the drug from the reservoir; and

a transducer connected to the chamber, wherein the transducer transdermally delivers the drug from the chamber to skin of the user based on an electrical signal received from the signal generator.

2. The wearable device of claim 1, wherein the drug delivery unit further comprises a transdermal patch adhesively coupled to the skin of the user.

3. The wearable device of claim 1, wherein the transducer further comprises a piezoelectric plate, and wherein the piezoelectric plate generates ultrasonic vibrations based on the electrical signal received from the signal generator.

4. The wearable device of claim 1, wherein the processor is further configured to:

generate indicia based on the body parameter; and

generate a user interface for displaying the indicia.

5. The wearable device of claim 4, wherein the processing unit further comprises a screen, and wherein the screen displays the user interface.

6. The wearable device of claim 1, further comprising a wrist band configured to be worn by a user, wherein the processing unit and the drug delivery unit are disposed on the wrist band.

7. The wearable device of claim 1, further comprising a communication interface to communicably couple the processor with the transducer.

8. The wearable device of claim 1, further comprising a drug tube, wherein the drug tube delivers the determined quantity of the drug from the reservoir to the chamber.

9. The wearable device of claim 1, wherein the processing unit further comprises a pump to regulate discharge of the drug from the reservoir based on the determined quantity of the drug.

10. A wearable device for delivering a drug, the wearable device comprising:

a band configured to be detachably attached to a user;

a processing unit disposed on the band, the processing unit comprising;

a sensor configured to determine a body parameter of a user;

a reservoir to store the drug;

a processor communicably coupled to the sensor, wherein the processor receives a signal indicative of the body parameter from the sensor, and wherein the processor determines a quantity of the drug to be delivered from the reservoir based on the body parameter; and

a signal generator to generate electrical signals based on control instructions received from the processor; and

a drug delivery unit disposed on the band and connected to the processing unit, the drug delivery unit comprising;

a chamber to receive the determined quantity of the drug from the reservoir; and

a transducer connected to the chamber, wherein the transducer transdermally delivers the drug from the chamber to skin of the user based on an electrical signal received from the signal generator.

11. The wearable device of claim 10, wherein the drug delivery unit further includes a transdermal patch adhesively coupled to the skin of the user.

12. The wearable device of claim 10, wherein the transducer further comprises a piezoelectric plate, and wherein the piezoelectric plate generates ultrasonic vibrations based on the electrical signal received from the signal generator.

13. The wearable device of claim 10, wherein the processing unit further comprises a pump to regulate discharge of the drug from the reservoir based on the determined quantity of the drug.

14. The wearable device of claim 10, wherein the processor is further configured to:

generate indicia based on the body parameter; and

generate a user interface for displaying the indicia.

15. The wearable device of claim 14, wherein the processing unit further comprises a screen to display the user interface.

16. The wearable device of claim 10, further comprising a communication interface disposed within the band, wherein the communication interface communicably couples the processor with the transducer.

17. A wearable device for delivering a drug, the wearable device comprising:

a band worn on a wrist of a user;

a processing unit connected to the band, the processing unit comprising;

a sensor configured to determine a body parameter of a user;

a reservoir to store the drug;

a processor communicably coupled to the sensor, wherein the processor receives a signal indicative of the body parameter from the sensor, and wherein the processor determines a quantity of the drug to be delivered from the reservoir based on the body parameter;

a pump to regulate discharge of the drug from the reservoir based on the determined quantity of the drug; and

a signal generator to generate electrical signals based on control instructions received from the processor; and

a drug delivery unit connected to the band, the drug delivery unit comprising;

a chamber to receive the determined quantity of the drug from the reservoir; and

a transducer connected to the chamber, wherein the transducer transdermally delivers the drug from the chamber to skin of the user based on an electrical signal received from the signal generator.

18. The wearable device of claim 17, wherein the processor:

generates indicia based on the body parameters; and

generates a user interface for displaying the indicia.

19. The wearable device of claim 17, further comprising a communication interface disposed within the band, wherein the communication interface communicably couples the processor with the transducer.

20. The wearable device of claim 17, further comprising a drug tube disposed within the band, wherein the drug tube delivers the determined quantity of the drug from the reservoir to the chamber.