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Swallowable drug delivery device and method of delivery

  • US 10,039,908 B2
  • Filed: 10/06/2014
  • Issued: 08/07/2018
  • Est. Priority Date: 12/24/2009
  • Status: Active Grant
First Claim
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1. A method for delivering a therapeutic agent into a wall of the small intestine of a patient, the method comprising:

  • swallowing a drug delivery device comprising a capsule, an expandable member and a therapeutic agent preparation shaped as a solid tissue penetrating member, the tissue penetrating member coupled to the expandable member by an advancement member that advances the tissue penetrating member into the wall of the small intestine upon expansion of the expandable member, an end of the advancement member detachably engaging a non-tissue penetrating end of the tissue penetrating member, wherein the end of the advancement member engaging the tissue penetrating member has a larger horizontal surface area than the non-tissue penetrating end of the tissue penetrating member; and

    expanding the expandable member responsive to a condition in the small intestine to apply a force to a solid surface of the tissue penetrating member using the advancement member so as to insert the tissue penetrating member into the wall of the small intestine where it remains and degrades to release the therapeutic agent into the patient'"'"'s blood stream.

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