Electrode configuration for a biosensor

• US 10,041,901 B2
• Filed: 03/15/2013
• Issued: 08/07/2018
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Inventors: Riggles, Randall K., Joseph, Abner D., Carpenter, Scott E., Buck, Jr., Harvey E., Lica, Georgeta C., Beaty, Terry A.
• Primary Examiner(s): Kessel, Maris R
• Application Number:
  US13/837,083
• Publication Number:
  US 20140262773A1
• Time in Patent Office: 1,971 Days
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

A biosensor including a capillary chamber having an inner boundary, a working electrode including an effective working electrode portion positioned within the capillary chamber, and a counter electrode including an effective counter electrode portion positioned within the capillary chamber, and with the working and counter electrodes each having a neck that constitutes the sole portion of the electrodes that extends across the inner boundary and out of the capillary chamber. In one embodiment, the effective working electrode portion defines an average working electrode width, and the working electrode neck defines a working electrode neck width that is reduced relative to the average working electrode width. In another embodiment, a ratio between the area of the effective working electrode portion exposed to the capillary chamber and the area of the effective counter electrode portion exposed to the capillary chamber is substantially constant as a position of the inner boundary of the capillary chamber is varied along a length of the working and counter electrode necks.

Claims

1. A biosensor, comprising:

a capillary chamber having an inner boundary;

a working electrode including an effective working electrode portion positioned within the capillary chamber and comprising a main working electrode body portion and a working electrode neck extending from the main working electrode body portion, the main working electrode body portion having a generally linear configuration having an average width and the working electrode neck having a working electrode neck width that is reduced relative to the average width of the main working electrode body portion, the working electrode neck constituting the sole portion of the working electrode that extends across the inner boundary and out of the capillary chamber wherein the effective working electrode portion defines an effective working electrode area exposed to the capillary chamber including the entire area of the main working electrode body portion and an area of the working electrode neck contained within the capillary chamber; and

a counter electrode including an effective counter electrode portion positioned within the capillary chamber and comprising a main counter electrode body portion and a counter electrode neck extending from the main counter electrode body portion, the counter electrode neck having a counter electrode neck width, the counter electrode neck constituting the sole portion of the counter electrode that extends across the inner boundary and out of the capillary chamber wherein the effective counter electrode portion defines an effective counter electrode area exposed to the capillary chamber including the entire area of the main counter electrode body portion and an area of the counter electrode neck contained within the capillary chamber,

wherein the working electrode neck width is less than the counter electrode neck width, wherein the effective working electrode area is different than the effective counter electrode area,

wherein the working electrode neck extends across a single inner side wall of the inner boundary of the capillary chamber and the counter electrode neck extends across the same single inner side wall of the inner boundary of the capillary chamber, and

wherein a ratio between the effective working electrode area and the effective counter electrode area is independent of the relative position of the inner side wall along the reduced working electrode neck width.

2. The biosensor of claim 1, wherein the working electrode neck width is no more than one-half of the counter electrode neck width.

3. The biosensor of claim 1, wherein the working electrode neck width is no more than 80% of the average working electrode width.

4. The biosensor of claim 1, wherein the effective working electrode area is less than the effective counter electrode area.

5. The biosensor of claim 1,

wherein a first ratio between the effective working electrode area and the working electrode neck width is substantially equal to a second ratio between the effective counter electrode area and the counter electrode neck width.

6. The biosensor of claim 5, wherein the effective working electrode area is less than the effective counter electrode area.

7. The biosensor of claim 1, wherein the single inner side wall defining the inner boundary of the capillary chamber comprises a lateral side wall extending across a width of the biosensor.

8. The biosensor of claim 1, further comprising:

a support substrate including a first inner surface with the working and counter electrodes extending along the first inner surface; and

a spacer substrate including a first face and an opposite second face, the spacer substrate defining the inner boundary of the capillary chamber, the first face of the spacer substrate attached to the first inner surface of the support substrate.

9. The biosensor of claim 8, further comprising a cover substrate including a second inner surface attached to the second face of the spacer substrate;

and

wherein the capillary chamber is defined by overlapping portions of the first inner surface of the support substrate and the second inner surface of the cover substrate in combination with the inner boundary defined by the spacer substrate.

10. The biosensor of claim 8, wherein the spacer substrate includes a channel extending therethrough from the first face to the second face, the channel defining the inner boundary of the capillary chamber.

11. The biosensor of claim 8, wherein the support substrate has a length dimension extending generally along a longitudinal axis and a width dimension extending generally along a transverse axis;

wherein the working electrode neck and the counter electrode neck each extend in a direction generally along the longitudinal axis.

12. The biosensor of claim 8, wherein the support substrate has a length dimension extending generally along a longitudinal axis and a width dimension extending generally along a transverse axis;

and

wherein the working electrode neck and the counter electrode neck each extend across a single inner side wall defining the inner boundary of the capillary chamber, the single inner side wall extending generally along the transverse axis.

13. The biosensor of claim 12, wherein the effective working electrode portion includes a main body extending generally along the transverse axis and with the working electrode neck extending from the main body generally along the longitudinal axis.

14. The biosensor of claim 13, wherein the effective counter electrode portion includes a loop body extending peripherally about the main body of the effective working electrode portion and with the counter electrode neck extending from the loop body generally along the longitudinal axis.

15. A biosensor, comprising:

a capillary chamber having an inner boundary;

a working electrode including an effective working electrode portion positioned within the capillary chamber and comprising a main working electrode body portion with a working electrode neck extending therefrom, the working electrode neck having a reduced width relative to the main working electrode body portion and constituting the sole portion of the working electrode that extends across the inner boundary and out of the capillary chamber; and

a counter electrode including an effective counter electrode portion positioned within the capillary chamber and comprising a main counter electrode body portion with a counter electrode neck extending therefrom, the main counter electrode body portion positioned generally adjacent the main working electrode body portion, the counter electrode neck constituting the sole portion of the counter electrode that extends across the inner boundary and out of the capillary chamber,

wherein the effective working electrode portion defines an effective working electrode area exposed to the capillary chamber including the entire area of the main working electrode body portion and an area of the working electrode neck contained within the capillary chamber,

wherein the effective counter electrode portion defines an effective counter electrode area exposed to the capillary chamber including the entire area of the main counter electrode body portion and an area of the counter electrode neck contained within the capillary chamber,

wherein the effective working electrode area is different than the effective counter electrode area,

wherein the reduced width of the working electrode neck is less than a width of the counter electrode neck width,

wherein the working electrode neck extends across a single inner side wall of the inner boundary of the capillary chamber and the counter electrode neck extends across the same single inner side wall of the inner boundary of the capillary chamber, and

wherein a ratio between the effective working electrode area and the effective counter electrode area is independent of the relative position of the inner side wall along the reduced width of the working electrode neck.

16. The biosensor of claim 15, wherein the main body of the effective counter electrode portion has a loop configuration extending peripherally about the main body of the effective working electrode portion.

17. The biosensor of claim 15, wherein the main body of the effective working electrode portion and the working electrode neck cooperate with one another to provide the effective working electrode portion with a T-shaped configuration.

18. The biosensor of claim 17, wherein the main body of the effective counter electrode portion has a C-shaped configuration extending peripherally about the T-shaped configuration of the effective working electrode portion.

19. The biosensor of claim 15,

wherein a first ratio between the effective working electrode area and a width of the working electrode neck is substantially equal to a second ratio between the effective counter electrode area and a width of the counter electrode neck.

20. The biosensor of claim 15, wherein the single inner side wall defining the inner boundary of the capillary chamber comprises a lateral side wall extending across a width of the biosensor.

21. The biosensor of claim 15, further comprising:

a support substrate including a first inner surface with the working and counter electrodes extending along the first inner surface, the support substrate having a length dimension extending generally along a longitudinal axis and a width dimension extending generally along a transverse axis; and

a spacer substrate including a first face and an opposite second face, the spacer substrate including one or more inner side walls defining the inner boundary of the capillary chamber, the first face of the spacer substrate attached to the first inner surface of the support substrate; and

wherein the working electrode neck and the counter electrode neck each extend generally along the longitudinal axis and across a single inner side wall defining the inner boundary of the capillary chamber, the single inner side wall extending generally along the transverse axis.

22. A biosensor, comprising:

a capillary chamber having an inner boundary;

a working electrode including an effective working electrode portion positioned within the capillary chamber and comprising a main working electrode body portion and a working electrode neck extending from the main working electrode body portion wherein the effective working electrode portion defines an effective working electrode area exposed to the capillary chamber including the entire area of the main working electrode body portion and an area of the working electrode neck contained within the capillary chamber, the working electrode neck having a reduced width relative to the main working electrode body portion and being the sole portion of the working electrode that extends out of the capillary chamber; and

a counter electrode including an effective counter electrode portion positioned within the capillary chamber and comprising a main counter electrode body portion and a counter electrode neck extending from the main counter electrode body portion wherein the effective counter electrode portion defines an effective counter electrode area exposed to the capillary chamber including the entire area of the main counter electrode body portion and an area of the counter electrode neck contained within the capillary chamber, the counter electrode neck being the sole portion of the counter electrode that extends out of the capillary chamber, and

wherein the working electrode neck extends across a single inner side wall of the inner boundary of the capillary chamber and the counter electrode neck extends across the same single inner side wall of the inner boundary of the capillary chamber,

wherein the effective working electrode area is different than the effective counter electrode area,

wherein the reduced width of the working electrode neck is less than a width of the counter electrode neck, and

wherein a ratio between the effective working electrode area and the effective counter electrode area is independent of the relative position of the inner side wall along the reduced width of the working electrode neck.

23. The biosensor of claim 22, wherein the effective working electrode area is less than the effective counter electrode area.

24. The biosensor of claim 22,

wherein a first ratio between the effective working electrode area and the working electrode neck width is substantially equal to a second ratio between the effective counter electrode area and the counter electrode neck width.

25. The biosensor of claim 24, wherein the effective working electrode area is less than the effective counter electrode area.