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Methods and kits for predicting a response to an erythropoietic agent

  • US 10,041,956 B2
  • Filed: 05/14/2015
  • Issued: 08/07/2018
  • Est. Priority Date: 06/23/2010
  • Status: Active Grant
First Claim
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1. A method for predicting a response to an erythropoietic agent in a subject, comprising:

  • (a) providing a biological sample from a subject who has been previously administered a dose amount of an erythropoietic agent;

    (b) measuring an amount in the sample of the peptide consisting of SEQ ID NO;

    15;

    (c) comparing the amount of the peptide in the sample to a control level of the peptide;

    (d) predicting that the subject will have a poor response to the erythropoietic agent when there is a measurable increase in the amount of the peptide consisting of SEQ ID NO;

    15 in the sample as compared to the control level; and

    (e) modifying the dose amount of the erythropoietic agent being administered to the subject by administering an increased dose amount of the erythropoietic agent to the subject predicted to have a poor response to the erythropoietic agent in (d), wherein the increased dose amount of the erythropoietic agent is increased as compared to the dose amount of the erythropoietic agent previously administered to the subject.

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