Ametropia treatment tracking methods and system

• US 10,042,181 B2
• Filed: 01/27/2016
• Issued: 08/07/2018
• Est. Priority Date: 01/27/2016
• Status: Active Grant

• Current Assignee: Johnson & Johnson Vision Care Incorporated (Johnson & Johnson)
• Original Assignee: Johnson & Johnson Vision Care Incorporated (Johnson & Johnson)
• Inventors: Brennan, Noel A., Chehab, Khaled, Ritchey, Eric R., Jones-Jordan, Lisa A., Sinnott, Loraine T., Cheng, Xu
• Primary Examiner(s): SCHWARTZ, JORDAN MARC
• Application Number:
  US15/007,660
• Publication Number:
  US 20170209036A1
• Time in Patent Office: 923 Days
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models
• CPC Class Codes: A61B 3/0033 characterised by user input arrangements
• CPC Class Codes: A61B 3/0058 for multiple images
• CPC Class Codes: A61B 3/103 for determining refraction, e.g. refractometers, skiascopes
• CPC Class Codes: G02C 2202/24 Myopia progression prevention
• CPC Class Codes: G02C 7/024 Methods of designing ophthalmic lenses
• CPC Class Codes: G02C 7/027 considering wearer's parameters
• CPC Class Codes: G02C 7/04 Contact lenses for the eyes disinfection or sterilisation of contact lenses A61L12/00
• CPC Class Codes: G16H 20/00 ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients

Abstract

A method for estimating and tracking refractive error progression of an individual includes estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual'"'"'s age by comparison to a reference population; estimating an expected SPHEQ trajectory over a future predetermined period of time; comparing the expected SPHEQ trajectory with the reference population; and comparing the expected SPHEQ trajectory with an expected SPHEQ trajectory using an ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time.

Claims

1. A method for estimating and tracking refractive error progression of an individual over a predetermined period of time to determine the effectiveness of treatment, comprising:

estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual'"'"'s age by comparison to a reference population;

estimating an expected SPHEQ trajectory of the individual over a future predetermined period of time using a predetermined set rate of change;

determining an expected SPHEQ trajectory using an ametropia control treatment;

comparing the estimated expected SPHEQ trajectory to the estimated percentile of SPHEQ; and

comparing the estimated expected SPHEQ trajectory with the expected SPHEQ trajectory using the ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time using the comparisons to estimate and track refractive error progression of the individual, using the comparisons to determine a potential treatment benefit over the predetermined period of time for the patient, and using the comparisons to manufacture ophthalmic lenses that provide the potential treatment benefit.

2. A method according to claim 1, further comprising estimating probabilities of errors of the expected SPHEQ trajectory over the predetermined period of time.

3. A method according to claim 1, further comprising:

measuring actual SPHEQ refraction history for the individual and comparing to a reference population; and

estimating an updated expected SPHEQ trajectory.

4. A method according to claim 1, further comprising:

measuring actual SPHEQ refraction history for the individual while using a given ametropia control treatment and comparing to a reference population; and

estimating an updated expected SPHEQ trajectory, thereby showing actual treatment benefit over a predetermined period of time.

5. A method according to claim 1, wherein said estimating a percentile of SPHEQ comprises modeling population reference percentiles of SPHEQ from a selected dataset comprising Spherical Equivalent Refraction data as a function of age and at least one of country, region, gender, ethnicity, or parental history.

6. A method according to claim 5, wherein the population reference percentiles comprise curves in selected percentile increments.

7. A method according to claim 1, wherein said estimating an expected SPHEQ trajectory over a future predetermined period of time is a function of a baseline age of the individual and a baseline SPHEQ.

8. A method according to claim 1, wherein said estimating an expected SPHEQ trajectory over a future predetermined period of time is a function of a baseline age of the individual, a baseline SPHEQ, and past refractive history.

9. A method according to claim 8, wherein the past refractive history comprises a progression rate of between 0.5 D to 1.5 D per year.

10. A method according to claim 1, wherein the ametropia control treatment comprises a myopia control ophthalmic lens.

11. A method according to claim 10, wherein the myopia control ophthalmic lens comprises a myopia control contact lens.

12. A method according to claim 1, further comprising displaying a comparison of the expected SPHEQ trajectory over the future predetermined period of time with the expected SPHEQ trajectory using the ametropia control treatment.

13. A method according to claim 12, wherein said displaying is on a graphical user interface of a smart device.

14. A method according to claim 4, further comprising:

measuring actual SPHEQ refraction history for the individual while using a given ametropia control treatment at periodic intervals;

estimating an updated expected SPHEQ trajectory at each interval; and

saving data comprising the updated expected SPHEQ trajectory at each interval to a secure server or database.

15. A method according to claim 14, further comprising providing access to a user authorized to view said saved data.

16. A method according to claim 14, wherein said authorized user comprises at least one of an Eye Care Provider, customer, parent, or child.

17. A method according to claim 14, further comprising:

providing said saved data to a third party, said data comprising age and SPHEQ refraction measurements; and

updating a database comprising clinical data on efficacy of the ametropia control treatment.

18. A method according to claim 14, further comprising saving data for a plurality of children and/or for a plurality of ametropia treatment options.

19. A computer program product for estimating and tracking refractive error progression of an individual over a predetermined period of time to determine the effectiveness of treatment, comprising:

a non-transitory computer readable storage medium;

first program instructions for estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual'"'"'s age by comparison to a reference population;

second program instructions for estimating an expected SPHEQ trajectory of the individual over a future predetermined period of time using a predetermined set rate of change;

third program instructions for determining an expected SPHEQ trajectory using an ametropia control treatment;

fourth program instructions for comparing the estimated expected SPHEQ trajectory to the estimated percentile of SPHEQ; and

fifth program instructions for comparing the estimated expected SPHEQ trajectory with the expected SPHEQ trajectory using the ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time using the comparisons to estimate and track refractive error progression of the individual, using the comparisons to determine a potential treatment benefit over the predetermined period of time for the patient, and using the comparisons to manufacture ophthalmic lenses that provide the potential treatment benefit,

wherein the first, second, third, fourth and fifth program instructions are stored on said non-transitory computer readable storage medium.