System and method for real-time frequency correction for magnetic resonance imaging

• US 10,045,741 B2
• Filed: 08/01/2014
• Issued: 08/14/2018
• Est. Priority Date: 08/02/2013
• Status: Active Grant

• Current Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Original Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Inventors: Tisdall, Matthew, van der Kouwe, Andre
• Primary Examiner(s): Vargas, Dixomara
• Application Number:
  US14/449,297
• Publication Number:
  US 20150035530A1
• Time in Patent Office: 1,474 Days
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: G01R 33/5616 using gradient refocusing, e.g. EPI
• CPC Class Codes: G01R 33/565 Correction of image distortions, e.g. due to magnetic field inhomogeneities
• CPC Class Codes: G01R 33/56509 due to motion, displacement or flow, e.g. gradient moment nulling G01R33/567 takes precedence
• CPC Class Codes: G01R 33/56518 due to eddy currents, e.g. caused by switching of the gradient magnetic field
• CPC Class Codes: G01R 33/56563 caused by a distortion of the main magnetic field B0, e.g. temporal variation of the magnitude or spatial inhomogeneity of B0 G01R33/56509, G01R33/56518, G01R33/56536 take precedence

Abstract

Systems and methods for estimating frequency drifts in magnetic resonance signals acquired with a magnetic resonance imaging (“MRI”) system are provided. In one example, the frequency drifts are estimated from phase-correction data that are obtained during an echo-planar imaging (“EPI”), or other multiecho imaging, scan. The systems and methods of the present invention provide for efficiently and accurately computing frequency drift values that can be used for real-time, prospective frequency drift correction.

Claims

1. A method for estimating frequency-drift errors in a magnetic resonance signal acquired with a magnetic resonance imaging (MRI) system, the steps of the method comprising:

a) acquiring data with the MRI system by directing the MRI system to perform a pulse sequence that samples multiple echo signals in each repetition time (TR) period;

b) selecting reference data from the acquired data using a computer system;

c) computing with the computer system, phase offset values based on the acquired data and the selected reference data, wherein the phase offset values are related to a frequency drift in data acquired during a given TR period relative to the selected reference data; and

d) estimating with the computer system, a frequency drift value from the computed phase offset values.

2. The method as recited in claim 1 further comprising correcting with the computer system, the acquired data for errors associated with the frequency drift using the estimated frequency drift value.

3. The method as recited in claim 1 wherein the reference data is selected using the computer system as data acquired in a first TR period.

4. The method as recited in claim 1 wherein step c) includes mitigating phase variations in the acquired data using the computer system before computing the phase offset value.

5. The method as recited in claim 4 in which the phase variations are mitigated by pointwise multiplying the acquired data for a given TR period by a conjugate of the reference data using the computer system.

6. The method as recited in claim 1 wherein step c) includes computing phase offset data with the computer system by pointwise multiplying each line of data by a conjugate of that line of data shifted by one line in a direction corresponding to gradient blips applied during data acquisition in step a).

7. The method as recited in claim 6 wherein step c) includes mitigating phase variations in the acquired data using the computer system before computing the phase offset data using the computer system.

8. The method as recited in claim 7 wherein the phase variations are mitigated using the computer system by pointwise multiplying the acquired data for a given TR period by a conjugate of the reference data.

9. The method as recited in claim 6 wherein the phase offset value is computed using the computer system by calculating a complex average of the phase offset data and computing a phase value of the complex averaged phase offset data.

10. The method as recited in claim 1 wherein step d) includes dividing the phase offset value by an echo spacing time implemented during data acquisition in step a) using the computer system.

11. The method as recited in claim 1 wherein data is acquired with the MRI system in step a) using an echo-planar imaging pulse sequence.

12. The method as recited in claim 1 wherein data is acquired with the MRI system in step a) using a pulse sequence that includes acquiring volumetric navigator data.

13. The method as recited in claim 2, further comprising reconstructing with the computer system, an image from the acquired data that has been corrected for errors associated with the frequency drift using the estimated frequency drift value, wherein the image has reduced errors associated with the frequency drift as compared to an image reconstructed from the acquired data without correcting for errors associated with the frequency drift.