Magnetic resonant imaging safe stylus

• US 10,046,165 B2
• Filed: 04/21/2015
• Issued: 08/14/2018
• Est. Priority Date: 04/21/2014
• Status: Active Grant

• Current Assignee: George Mason University, University of South Florida (State University System of Florida)
• Original Assignee: University of South Florida (State University System of Florida)
• Inventors: Frewin, Christopher Leroy, Register, Joseph Jonathan, Saddow, Stephen E., Reyes-Natal, Meralys, Pancrazio, Joseph J.
• Primary Examiner(s): MISHLER, ROBIN J
• Application Number:
  US15/303,545
• Publication Number:
  US 20170050029A1
• Time in Patent Office: 1,211 Days
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/6868 Brain
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation

Abstract

An implantable magnetic resonant imaging (MRI) safe stylus for biomedical devices is described. In one example, the stylus includes a set of stylus modules. One or more of the stylus modules includes a core rod formed of silicon carbide (SiC) material, a recording array mounted on the core rod, and a stimulation array mounted at a distal end of the core rod. The stylus also includes a hemispherical cap formed of SiC material. In part due to the construction and choice of materials used in the stylus, it does not substantially couple with electromagnetic fields during an MRI, for example. Therefore, the stylus does not produce excessive additional heat. The designs described herein also rely on the high thermal transport but low heat capacity of SiC to provide a thermal pathway which will conduct induced heat throughout the stylus, to dissipate heat more evenly.

Claims

1. A stylus, comprising:

a plurality of stylus modules, at least one of the plurality of stylus modules comprising;

a core rod formed of silicon carbide (SiC) material that extends a distance along a longitudinal axis of the core rod;

a recording array mounted on at least a portion of a peripheral surface of the core rod that extends substantially in a direction of the longitudinal axis of the core rod, the recording array comprising at least one electrode formed through ion implantation of a doped substrate of SiC material; and

a stimulation array mounted at a distal end of the core rod, the stimulation array including at least one stimulation electrode that extends at least in part perpendicularly to the direction of the longitudinal axis of the core rod;

a hemispherical cap formed of SiC material positioned proximate to a distal end of one of the plurality of stylus modules; and

a hermetic seal that seals the plurality of stylus modules from exposure to body tissue.

2. The stylus of claim 1, wherein the core rod comprises:

a groove in the peripheral surface of the core rod that extends substantially in the direction of the longitudinal axis; and

a central aperture that extends through a center of the core rod substantially in the direction of the longitudinal axis.

3. The stylus of claim 2, further comprising:

a stimulation lead that extends through the central aperture of the core rod and is electrically coupled to the stimulation array at one distal end; and

a recording lead that extends in the groove of the core rod and is electrically coupled to the recording array at one distal end.

4. The stylus of claim 3, wherein an insulator of at least one of the stimulation lead and the recording lead is impregnated with SiC nanoparticles.

5. The stylus of claim 3, wherein:

the stimulation array includes a central aperture formed through a center of the stimulation array, the central aperture including peripheral edge notch cutouts;

the stimulation lead extends to the central aperture of the stimulation array and is electrically coupled to the stimulation array at the central aperture; and

the core rod includes tabs which extend through the peripheral edge notch cutouts of the stimulation array and mechanically mate into the hemispherical cap.

6. The stylus of claim 1, wherein:

the recording array comprises a plurality of recording electrodes; and

each of the plurality of recording electrodes comprises an electrode and associated isolation ring formed through ion implantation of a doped substrate of SiC material.

7. The stylus of claim 6, wherein the recording array further comprises a planar metal contact and planar lead trace for each of the plurality of recording electrodes.

8. The stylus of claim 1, wherein the hermetic seal is formed from a coating of amorphous SiC deposited using chemical vapor deposition.

9. A stylus module, comprising:

a core rod formed of silicon carbide (SiC) material that extends a distance along a longitudinal axis of the core rod;

a recording array comprising a plurality of recording electrodes mounted on at least a portion of a peripheral surface of the core rod, wherein each of the plurality of recording electrodes comprises an electrode formed through ion implantation of a doped substrate of SiC material and respectively extend substantially in a direction of a longitudinal axis of the core rod;

a stimulation array mounted at a distal end of the core rod; and

a hermetic seal that seals the core rod and recording array from exposure to body tissue.

10. The stylus module of claim 9, wherein the core rod comprises:

a groove in a peripheral surface of the core rod that extends substantially in a direction of the longitudinal axis; and

a central aperture that extends through a center of the core rod substantially in the direction of the longitudinal axis.

11. The stylus module of claim 10, further comprising:

a stimulation lead that extends through the central aperture of the core rod and is electrically coupled to the stimulation array at one distal end; and

a recording lead that extends in the groove of the core rod and is electrically coupled to the recording array at one distal end.

12. The stylus module of claim 11, wherein an insulator of at least one of the stimulation lead and the recording lead is impregnated with SiC nanoparticles.

13. The stylus module of claim 11, wherein:

the stimulation array includes a central aperture formed through a center of the stimulation array, the central aperture including peripheral edge notch cutouts; and

the stimulation lead extends to the central aperture of the stimulation array and is electrically coupled to the stimulation array at the central aperture.

14. The stylus module of claim 9, wherein the recording array further comprises a planar metal contact and planar lead trace for each of the plurality of recording electrodes.

15. The stylus module of claim 9, wherein the hermetic seal is formed from a coating of amorphous SiC deposited using chemical vapor deposition.

16. The stylus module of claim 9, further comprising a hemispherical cap formed of SiC material positioned proximate to a distal end of the core rod.

17. A stylus, comprising:

a plurality of stylus modules, at least one of the plurality of stylus modules comprising;

a core rod formed of silicon carbide (SiC) material that extends a distance along a longitudinal axis of the core rod;

a recording array comprising a plurality of recording electrodes mounted on at least a portion of a peripheral surface of the core rod, wherein each of the plurality of recording electrodes comprises an electrode formed through ion implantation of a doped substrate of SiC material; and

a stimulation array formed of SiC material, the stimulation array including at least one stimulation electrode;

a hemispherical cap formed of SiC material positioned proximate to a distal end of one of the plurality of stylus modules; and

a hermetic seal that seals the plurality of stylus modules from exposure to body tissue.

18. The stylus of claim 17, further comprising:

a stimulation lead that is electrically coupled to the stimulation array; and

a recording lead that is electrically coupled to the recording array, wherein an insulator of at least one of the stimulation lead and the recording lead is impregnated with SiC nanoparticles.

19. The stylus of claim 18, wherein:

the stimulation array includes a central aperture formed through a center of the stimulation array; and

the stimulation lead extends to the central aperture of the stimulation array and is electrically coupled to the stimulation array at the central aperture.

20. The stylus of claim 18, wherein the hermetic seal is formed from a coating of amorphous SiC deposited using chemical vapor deposition.