×

Oscillating immunoassay method and device

  • US 10,048,258 B2
  • Filed: 03/31/2016
  • Issued: 08/14/2018
  • Est. Priority Date: 08/05/2010
  • Status: Active Grant
First Claim
Patent Images

1. A method of performing a sandwich immunoassay for an analyte, said method comprising:

  • mixing magnetically susceptible beads with a sample containing an analyte, wherein the beads are coated with a first antibody to the analyte and a signaling moiety;

    oscillating the beads across the surface of a sensing electrode in an immunosensor coated with a second antibody to the analyte, thereby forming an antibody sandwich and immobilizing the beads on the immunosensor,wherein the sensing electrode is position in a conduit for receiving the sample containing the analyte mixed with the beads,wherein the conduit comprises two magnetic zones, andwherein the beads are oscillated in the direction of a capture motion of the beads;

    washing unbound sample and beads from the immunosensor; and

    detecting the signaling moiety immobilized on said immunosensor.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×