Sensor, gas analyzer and method for measuring concentration of at least one respiratory gas component

• US 10,052,025 B2
• Filed: 03/25/2013
• Issued: 08/21/2018
• Est. Priority Date: 03/26/2012
• Status: Active Grant

• Current Assignee: GE Healthcare Finland OY (General Electric Company)
• Original Assignee: GE Healthcare Finland OY (General Electric Company)
• Inventors: Haveri, Heikki Antti Mikael
• Primary Examiner(s): Carey, Michael
• Assistant Examiner(s): Ho, Don N
• Application Number:
  US13/849,578
• Publication Number:
  US 20130253336A1
• Time in Patent Office: 1,975 Days
• CPC Class Codes: A61B 2560/0209 adapted for power saving
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61M 16/0816 Joints or connectors
• CPC Class Codes: A61M 16/0858 Pressure sampling ports
• CPC Class Codes: A61M 16/1055 bacterial
• CPC Class Codes: A61M 16/1065 in the expiratory path
• CPC Class Codes: A61M 2016/0033 electrical
• CPC Class Codes: A61M 2016/1025 the O2 concentration
• CPC Class Codes: A61M 2016/103 the CO2 concentration
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2230/432 partial CO2 pressure (P-CO2)
• CPC Class Codes: A61M 2230/435 partial O2 pressure (P-O2)

Abstract

A sensor for measuring a concentration of a respiratory gas component is disclosed herein. The sensor comprises at least one radiation source configured to emit radiation and at least one radiation sensing detector configured to receive radiation and provide a signal indicative of the concentration of the gas component. The sensor further comprises an electronics board configured to receive and process the signal to determine the concentration, and an energy storage device configured to supply energy to the radiation source. The electronics board is configured to choose from among at least two different modes, one being an operation mode allowing sufficient energy supply to the radiation source, and another being a rest mode allowing reduced energy supply compared to the operation mode to limit radiation for saving energy within the breathing cycle. A gas analyzer and method for measuring a concentration of a respiratory gas component are also provided.

Claims

1. A sensor for measuring a concentration of at least one respiratory gas component in a breathing gas, which concentration is varying during a breathing cycle having an inspiration phase, an expiration phase and a phase between the inspiration and expiration, the sensor comprising:

at least one radiation source configured to emit radiation;

at least one radiation sensing detector configured to receive radiation and provide a signal indicative of the concentration of the at least one respiratory gas component;

an electronics board configured to receive and process the signal from the at least one radiation sensing detector to determine the concentration of the at least one respiratory gas component; and

an energy storage device configured to supply energy to the at least one radiation source;

wherein the electronics board is configured to choose from at least an operation mode providing sufficient energy supply to the at least one radiation source for subsequent concentration determination during a first time period, and a rest mode providing a reduced energy supply to the at least one radiation source during a second time period, wherein the operation mode is chosen when a derivative of a concentration of the at least one respiratory gas component approaches zero after a positive derivative peak, and the rest mode is chosen when the derivative decreases to a level below zero.

2. The sensor according to claim 1, wherein the electronics board is configured to choose the operation mode when the phase of the breathing cycle comprises one of at least part of the expiration and at least an end tidal volume of the expiration, and the electronics board is configured to choose the rest mode within one of the inspiration phase and the phase between the inspiration and expiration.

3. The sensor according to claim 1, wherein the electronics board is configured to choose the rest mode within the expiration phase excluding a plateau period when an end tidal volume of the expiration exists in which case the electronics board is configured to choose the operation mode.

4. The sensor according to claim 1, wherein the electronics board is configured to choose the operation mode to measure end-tidal values of gas concentrations and a fraction of inspired values, and configured to choose the rest mode during a portion of the time required by the breathing cycle when reduced accuracy in concentration determination is acceptable, and wherein a time period when the operation mode is valid is shorter than a time period when the rest mode is valid.

5. The sensor according to claim 1, further comprising at least one of a display configured to show breathing gas values measured, a user interface configured to operate the sensor, and a radio frequency transceiver configured to communicate with a host device.

6. The sensor according to claim 1, wherein at least one respiratory gas component is one of carbon dioxide and oxygen and the at least one radiation source emits radiation towards the breathing gas to measure the concentration of one of carbon dioxide and oxygen.

7. The sensor according to claim 1, wherein in the rest mode when reduced energy is configured to be supplied to the at least one radiation source, the at least one radiation source is configured to be either turned off, wherein at least one of (i) the electronics board is configured to pause energy supply to the at least one radiation source, and (ii) the at least one radiation source is configured to receive less energy than in the operation mode, but more than pausing energy supply where the electronics board is configured to adjust energy supply to the at least one radiation source to a lower operating power.

8. The sensor according to claim 1, further comprising a pressure detector configured to provide a signal indicative of the pressure of the breathing gas to the electronics board wherein the operation mode is chosen when a derivative of a the pressure approaches zero after a positive derivative peak in order to measure a fraction of inspired gas concentration values, and the rest mode is chosen when the derivative of the pressure decreases to a level below zero.

16. The sensor according to claim 1, wherein the first time period is shorter than said second time period.

19. The sensor according to claim 1, further comprising a flow detector configured to provide a signal indicative of the flow of the breathing gas to the electronics board, wherein choosing from among at least two different modes is based on a signal from the flow detector.

9. A gas analyzer for measuring a concentration of at least one respiratory gas component in a breathing gas, which concentration is varying during a breathing cycle having an inspiration phase, an expiration phase and a phase between the inspiration and expiration, the gas analyzer comprising:

an airway adapter comprising a sampling cell configured to allow the breathing gas flow, at least one optical component configured to guide radiation, wherein the optical component is in direct or indirect contact with the respiratory gas inside the sampling cell, a first port configured to deliver respiratory gas to the sampling cell, and a second port configured to remove respiratory gas from the sampling cell;

a sensor connectable to the airway adapter, the sensor comprising at least one radiation source configured to emit radiation towards the at least one optical component, at least one radiation sensing detector configured to receive for radiation and provide a signal indicative of the concentration of the at least one respiratory gas component, an electronics board configured to receive and process the signal from the at least one radiation sensing detector to determine the concentration of the at least one respiratory gas component, and an energy storage device configured to supply energy to the at least one radiation source;

wherein the electronics board is configured to choose from among at least an operation mode providing sufficient energy supply to the at least one radiation source for subsequent concentration determination during a first time period, and a rest mode providing a reduced energy supply to the at least one radiation source during a second time period, wherein the operation mode is chosen when a derivative of a concentration of the at least one respiratory gas component approaches zero after a positive derivative peak, and the rest mode is chosen when the derivative decreases to a level below zero.

10. The gas analyzer according to claim 9, wherein the sensor comprises at least one of a pressure detector and a flow detector, and the airway adapter comprises at least one of a pressure measuring component communicating with the pressure detector configured to provide a signal indicative of the pressure inside the airway adapter to the electronics board, and a flow measuring component communicating with the flow detector configured to provide a signal indicative of the flow through the airway adapter to the electronics board.

15. The gas analyzer according to claim 9, wherein the electronics board is configured to choose the operation mode when the phase of the breathing cycle comprises one of at least part of the expiration and at least an end tidal volume of the expiration, and the electronics board is configured to choose the rest mode within one of the inspiration phase and the phase between the inspiration and expiration.

17. The gas analyzer according to claim 9, wherein the first time period is shorter than said second time period.

11. A method for measuring a concentration of at least one respiratory gas component in a breathing gas, which concentration is varying during a breathing cycle having an inspiration phase, an expiration phase and a phase between the inspiration and expiration, the method comprising:

emitting radiation by at least one radiation source towards at least one optical component one of in direct and indirect contact with the respiratory gas inside a sampling cell,

receiving the radiation by at least one radiation sensing detector and providing from the at least one radiation sensing detector a signal indicative of the concentration of the at least one respiratory gas component;

receiving the signal from the at least one radiation sensing detector and processing the signal in an electronics board to determine the concentration of the at least one respiratory gas component;

supplying energy from an energy storage device to the at least one radiation source; and

choosing among at least an operation mode providing sufficient energy supply to the at least one radiation source for subsequent concentration determination during a first time period, and a rest mode providing a reduced energy supply to the at least one radiation source during a second time period, wherein the operation mode is chosen when a derivative of a concentration of the at least one respiratory gas component approaches zero after a positive derivative peak, and the rest mode is chosen when the derivative decreases to a level below zero.

12. The method according to claim 11, comprising choosing the rest mode within the expiration phase while excluding a plateau period when an end tidal volume of the expiration exists, and choosing the operation mode for the plateau period.

13. The method according to claim 11, comprising choosing the operation mode for measuring end-tidal values of gas concentrations and a fraction of inspired values and choosing the rest mode by the breathing cycle, and wherein a time period, when the operation mode is valid, is shorter than a time period when the rest mode is valid.

14. The method according to claim 11, comprising:

choosing the operation mode when the phase of the breathing cycle comprises one of at least part of the expiration and at least an end tidal volume of the expiration; and

choosing the rest mode within one of the inspiration phase and the phase between the inspiration and expiration.

18. The method according to claim 11, wherein the first time period is shorter than said second time period.