Implantable wireless accoustic stimulators with high energy conversion efficiencies

• US 10,052,493 B2
• Filed: 04/25/2016
• Issued: 08/21/2018
• Est. Priority Date: 03/25/2008
• Status: Active Grant

• Current Assignee: EBR Systems, Inc.
• Original Assignee: EBR Systems, Inc.
• Inventors: Moore, David F., Mohr, Paul, Willis, N. Parker, Brisken, Axel F.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US15/138,046
• Publication Number:
  US 20160310749A1
• Time in Patent Office: 848 Days
• Field of Search: None
• CPC Class Codes: A61B 2560/0214 of power generation or supply
• CPC Class Codes: A61N 1/02 Details
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/362 Heart stimulators heart defibrillators A61N1/39
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3758 Packaging of the components within the casing
• CPC Class Codes: A61N 1/3787 from an external energy source
• CPC Class Codes: H02N 2/181 Circuits; Control arrangements or methods
• CPC Class Codes: H02N 2/186 Vibration harvesters
• CPC Class Codes: H02N 2/188 adapted for resonant operation
• CPC Class Codes: H10N 30/03 Assembling devices that include piezoelectric or electrostrictive parts
• CPC Class Codes: H10N 30/30 with mechanical input and electrical output, e.g. functioning as generators or sensors
• CPC Class Codes: Y10T 29/42 Piezoelectric device making

Abstract

Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

Claims

1. An implantable receiver-stimulator for harvesting acoustic power from an acoustic field and generating electrical power, comprising:

a sealed enclosure with an inner and outer surface;

a first plurality of acoustic piezoelectric components which converts the acoustic field to electrical power, each piezoelectric component defined by a thickness and a base with a width and configured with the base mounted to the inner surface;

a plurality of individual rectifiers, where each rectifier is electrically connected to a corresponding piezoelectric component of the first plurality of piezoelectric components such that the electrical power from the piezoelectric components is converted by the rectifiers arranged in a circuit assembly to a biologically stimulating electrical output; and

at least two stimulation electrodes which receive the stimulating electrical output and deliver said output to tissue at sufficient electrical energy levels to stimulate the tissue;

wherein the acoustic piezoelectric components are distributed about the inner surface facing multiple directions such that the acoustic power is harvested efficiently from any direction of the propagating acoustic field; and

wherein at least part of the inner surface is configured as a circuit.

2. The device of claim 1, wherein the acoustic piezoelectric component is cuboid shaped.

3. The device of claim 1, wherein the circuit is a thin film dielectric with thin film metal conductors.

4. The device of claim 2, wherein the acoustic piezoelectric components and the rectifier circuitry are disposed on the circuit.

5. The device as in claim 4, wherein the acoustic piezoelectric components comprise a polycrystalline ceramic piezoelectric material or a single crystal piezoelectric material.

6. The device of claim 1, wherein the piezoelectric components are distributed on the inner surface of the enclosure to maximize the number of piezoelectric components that could be arranged inside the enclosure.

7. The device of claim 1, wherein the rectifier circuit assembly configures the rectifiers in parallel and comprises protection circuitry to protect the rectifiers from damage due to high voltages.

8. The device of claim 7, wherein the protection circuitry is configured to protect the rectifiers from voltages above approximately 4 V.

9. The device of claim 7, wherein the protection circuitry comprises a zener diode of a series or GaAs Schottky diodes.

10. The device of claim 1, wherein the rectifier circuit assembly comprises one or more rectifiers connected to the stimulation electrodes and circuitry to remove residual charge accumulated on the stimulation electrodes.

11. The device of claim 10, wherein the circuitry comprises a bleed resistor.

12. The device of claim 1, further comprising:

circuitry to limit said stimulating electrical output, thereby preventing harmful effects to the patient.

13. The device of claim 1, wherein the inner or outer surface is etched to form a plurality of apertures each defined by a width and length;

and the plurality of acoustic piezoelectric components are each affixed to the inner surface at a location of an etched acoustic aperture, wherein one or more of the etched acoustic apertures is larger than the widths and/or lengths of the piezoelectric components affixed to the aperture location.

14. The implantable stimulator of claim 13, wherein each piezoelectric component is configured to convert the impinging acoustic field into electrical power.

15. The implantable stimulator of claim 14, wherein the output from each piezoelectric component is rectified independently.

16. An implantable receiver-stimulator for harvesting acoustic power from an acoustic field and generating electrical power, comprising:

a sealed enclosure with an inner and outer surface;

a first plurality of acoustic piezoelectric components which converts the acoustic field to electrical power, each piezoelectric component defined by a thickness and a base with a width and configured with the base mounted to the inner surface;

a plurality of individual rectifiers, where each rectifier is electrically connected to a corresponding piezoelectric component of the first plurality of piezoelectric components such that the electrical power from the piezoelectric components is converted by the rectifiers arranged in a circuit assembly to a biologically stimulating electrical output; and

at least two stimulation electrodes which receive the stimulating electrical output and deliver said output to tissue at sufficient electrical energy levels to stimulate the tissue;

wherein the acoustic piezoelectric components are distributed about the inner surface facing multiple directions such that the acoustic power is harvested efficiently from any direction of the propagating acoustic field; and

wherein the sealed enclosure further comprises an end cap having a second plurality of acoustic piezoelectric components composed of a piezoelectric material, wherein the second plurality of acoustic piezoelectric components has a piezoelectric axis that is substantially perpendicular to that of the first plurality of piezoelectric components.

17. The device of claim 16, wherein the rectifier circuit assembly configures the rectifiers in parallel and comprises protection circuitry to protect the rectifiers from damage due to high voltages.

18. The device of claim 17, wherein the protection circuitry is configured to protect the rectifiers from voltages above approximately 4 V.

19. The device of claim 17, wherein the protection circuitry comprises a zener diode of a series or GaAs Schottky diodes.

20. The device of claim 16, wherein the rectifier circuit assembly comprises one or more rectifiers connected to the stimulation electrodes and circuitry to remove residual charge accumulated on the stimulation electrodes.