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System and method for estimating and manipulating estimated radiation dose

  • US 10,052,500 B2
  • Filed: 02/17/2016
  • Issued: 08/21/2018
  • Est. Priority Date: 06/22/2010
  • Status: Active Grant
First Claim
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1. A method, performed on a computer system, for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject, the achievable dose distribution estimate defined over a three-dimensional range of voxels with a dose value for each voxel, the method comprising:

  • (a) receiving, at the computer system, the achievable dose distribution estimate;

    (b) determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification;

    (c) for each beam from among a plurality of beams;

    (i) characterizing, by the computer system, the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and

    (ii) identifying, by the computer system, one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel;

    (d) modifying, by the computer system, the intensity values of at least one of the dose-change beamlets; and

    (e) updating, by the computer system, the achievable dose distribution estimate to account for the modified intensity values of the at least one of the dose-change beamlets.

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