Magnetic resonance imaging apparatus and magnetic resonance imaging method

• US 10,058,257 B2
• Filed: 11/03/2017
• Issued: 08/28/2018
• Est. Priority Date: 09/18/2009
• Status: Active Grant

• Current Assignee: Toshiba Medical Systems Corporation (Canon Inc.)
• Original Assignee: Toshiba Medical Systems Corporation (Canon Inc.)
• Inventors: Miyazaki, Mitsue, Kuhara, Shigehide
• Primary Examiner(s): TURCHEN, ROCHELLE DEANNA
• Application Number:
  US15/803,381
• Publication Number:
  US 20180055380A1
• Time in Patent Office: 298 Days
• CPC Class Codes: A61B 5/0037 Performing a preliminary scan, e.g. a prescan for identifying a region of interest
• CPC Class Codes: A61B 5/0263 using NMR
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/7271 Specific aspects of physiological measurement analysis A61B5/316, A61B5/349 and A61B5/374 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: G01R 33/385 using gradient magnetic field coils
• CPC Class Codes: G01R 33/4833 using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
• CPC Class Codes: G01R 33/543 Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription G01R33/546 takes precedence
• CPC Class Codes: G01R 33/5601 involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
• CPC Class Codes: G01R 33/5608 Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels image data processing or generation, in general G06T
• CPC Class Codes: G01R 33/5635 Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA]
• CPC Class Codes: G01R 33/56366 Perfusion imaging

Abstract

An MRI apparatus includes an imaging data acquiring unit and a blood flow information generating unit. The imaging data acquiring unit acquires imaging data from an imaging region including myocardium, without using a contrast medium, by applying a spatial selective excitation pulse to a region including at least a part of an ascending aorta for distinguishably displaying inflowing blood flowing into the imaging region. The blood flow information generating unit generates blood flow image data based on the imaging data.

Claims

1. A magnetic resonance imaging (MRI) apparatus comprising:

an assembly of gantry components including static and gradient magnetic field generators and at least one radio frequency (RF) coil; and

an MRI control system, connected to control the gantry components, including at least one RF transmitter, at least one RF receiver and one or more computer control circuits, the MRI control system being configured to;

apply a spatially non-selective inversion pulse and a spatially selective excitation pulse, for distinguishably displaying inflowing blood flowing into an imaging region including myocardium;

acquire a plurality of imaging data sets without administration of a contrast medium, each of the plurality of imaging data sets corresponding to a respective one of a plurality of different traveling times of inflowing blood flowing into the imaging region in synchronization with a heartbeat together with delay times form synchronization signals, by changing a time from application timing of the spatially selective excitation pulse to acquisition timing of each of the plurality of imaging data sets, wherein the delay times are set such that the time from application timing of the spatially selective excitation pulse to acquisition timing of each of the plurality of imaging data sets spans multiple heart beats for at least one of the acquisitions of the plurality of imaging data sets; and

generate a plurality of blood flow image data sets, based on the acquired plurality of imaging data sets,

wherein the MRI control system is further configured to set the delay times so as to include a first delay time and a second delay time, the first delay time being a time interval from a first R-wave to an application time of the spatially non-selective inversion pulse, and the second delay time being a time interval from a second R-wave immediately before data acquisition to a start time of the data acquisition.

2. The magnetic resonance imaging (MRI) apparatus according to claim 1,

wherein the MRI control system is further configured to:

apply a labeling pulse as the spatially excitation pulse to a region different from the imaging region; and

acquire the plurality of imaging data sets for distinguishably displaying the inflowing blood labeled by the labeling pulse.

3. The magnetic resonance imaging (MRI) apparatus according to claim 2,

wherein the MRI control system is further configured to apply the labeling pulse to the region including a coronary artery.

4. The magnetic resonance imaging (MRI) apparatus according to claim 2,

wherein the MRI control system is further configured to apply the labeling pulse to the region including one of a right coronary artery (RCA), a left main coronary trunk (LMT), a left circumflex artery (LCX), and a left anterior descending artery (LAD), but not including the other three.

5. The magnetic resonance imaging (MRI) apparatus according to claim 2,

wherein the MRI control system is further configured to apply the labeling pulse to a slab set inside a ventricle.

6. The magnetic resonance imaging (MRI) apparatus according to claim 2,

wherein the MRI control system is further configured to:

apply the spatially non-selective inversion pulse to the imaging region, while applying the labeling pulse to the region different from the imaging region; and

acquire the plurality of imaging data sets, by further applying an imaging region selective inversion recovery pulse to excite the imaging region selectively after applying the spatially non-selective inversion pulse and the labeling pulse.

7. The magnetic resonance imaging (MRI) apparatus according to claim 2,

wherein the MRI control system is further configured to:

acquire the plurality of imaging data sets by applying the spatially non-selective inversion pulse to the imaging region, while applying the labeling pulse to the region different from the imaging region; and

set an inversion recovery time from application timing of the spatially non-selective inversion pulse to acquisition timing of the plurality of imaging data sets and a time interval from application timing of the labeling pulse to the acquisition timing of the plurality of imaging data sets, changeably and independently each other.

8. The magnetic resonance imaging (MRI) apparatus according to claim 1,

wherein the MRI control system is further configured to apply a further spatially selective excitation pulse between the application timing of the spatially selective excitation pulse and the acquisition timing of each of acquisitions of the plurality of imaging data sets.

9. The magnetic resonance imaging (MRI) apparatus according to claim 1,

wherein the MRI control system is further configured to generate the plurality of blood flow image data sets, by performing correction to eliminate a signal component corresponding to a background of an image from the plurality of imaging data sets.