Device for occluding a lumen

• US 10,058,330 B2
• Filed: 05/11/2012
• Issued: 08/28/2018
• Est. Priority Date: 05/11/2011
• Status: Active Grant

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Microvention Incorporated (Terumo Corporation)
• Inventors: Fitz, Matthew, Tieu, Tai D., O'Leary, Shawn
• Primary Examiner(s): Shi, Katherine M
• Assistant Examiner(s): MENDOZA, MICHAEL G
• Application Number:
  US13/470,066
• Publication Number:
  US 20120316597A1
• Time in Patent Office: 2,300 Days
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 17/12181 formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids

Abstract

One embodiment according to the present invention includes an occlusion device in which the support structure or frame expands circumferentially within the lumen to secure an expansile plug or embolic material. Once in place, the expansile plug or embolic material expands, thereby occluding the target lumen. Another embodiment according to the present invention includes a radially expandable support structure having a closed portion for capturing subsequently delivered embolic material, such as embolic coils. For example, the structure may have a closed portion at its distal end or at its middle (forming an hourglass shape). Additionally, the closed portion may be formed from the support structure itself or from a discrete, second layer that is attached within the support structure.

Claims

1. An occlusion device comprising:

a stent comprising a woven tubular support structure having a compressed configuration and an expanded configuration, wherein said woven tubular support structure is configured to self-expand to said expanded configuration, forming a plurality of radially projecting loops on a proximal and distal end of said stent and forming an elongated passage therethrough terminating with a proximal opening and a distal opening;

a plug comprising hydrogel and having a compressed dehydrated state and an expanded hydrated state and self-expanding from a compressed configuration due to the presence of liquid to an expanded configuration the plug fixed within said tubular support structure, said plug compressed from an initial size prior to insertion within said stent and thus being of substantially smaller diameter than said woven tubular support structure when said tubular support structure is in said expanded configuration, said plug further utilizing a powdered visualization agent; and

,

a thread having a first end and a second end, and being skewered through substantially an entire length of said plug and around a wire of said woven tubular structure;

said first end being fixed to said second end to form a loop and so as to fix said plug to said woven tubular structure in both said compressed dehydrated state and in said expanded hydrated state and so as to maintain said thread from extending beyond said proximal opening and said distal opening.

2. An occlusion device comprising:

a stent comprising a woven tubular frame structure forming a passage therethrough;

said tubular frame structure having a compressed configuration and an expanded configuration, and a plurality of radially projecting loops at a proximal and distal end of said stent; and

a plug solely comprising expansile material in the form of hydrogel, having a compressed dehydrated state and an expanded, hydrated state;

the presence of a liquid causing said plug to expand, said plug compressed from an initial size prior to insertion within said stent and thus being of substantially smaller diameter than said woven tubular support structure when said tubular support structure is in said expanded configuration, said plug further utilizing a powdered visualization agent; and

,

a thread having a first end and a second end passing around a wire forming said woven tubular frame structure and fixing said plug within said passage in said compressed dehydrated state and in said expanded hydrated state;

said thread being skewered through substantially an entire length of said plug and said first end being fixed to said second end to form a loop and said thread only extending along a portion of said woven tubular frame structure.

3. The occlusion device of claim 2, wherein said tubular frame structure is formed from a single wire.