System and method for determining antibiotic effectiveness in respiratory diseased animals using auscultation analysis
First Claim
1. A method for determining effectiveness of an administered drug in treating a disease of a group of livestock using auscultation analysis, said method comprising:
- administering a first drug to a group of livestock;
conducting auscultations by an electronic stethoscopic device communicating with a computer processor to record auscultated sounds from the group of livestock;
determining, by said computer processor, a lung score corresponding to a respective level of severity of the disease for each livestock at the time of and based on the auscultations;
recording, in said computer processor, the first drug administered to the group of livestock;
recording, in said computer processor, fatalities for the group of livestock over a designated time period;
conducting, by said computer processor, a statistical analysis to determine whether there is a statistical difference in fatality rates between lung score categories;
analyzing, by said computer processor, the statistical analysis;
automatically determining, by said computer processor, a numerical relationship between fatality rates as a function of lung scores to determine effectiveness of the first drug, said automatically determining step includes;
generating a graphical comparison of fatality rates versus lung score categories, said comparison including a predicted probability line of the fatality rates as a function of the lung scores;
determining whether the first drug is effective or ineffective based on the slope of the predicted probability line, wherein the slope of the predicted probability line being positive indicates drug effectiveness and wherein the slope of said predicted probability line having a zero slope indicates drug ineffectiveness; and
administering a second different drug to the group of animals when the first drug is ineffective, or administering the first drug to the group of livestock when the first drug is effective.
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Accused Products
Abstract
A system and method are provided for diagnosis of animal respiratory diseases using auscultation techniques. Animal lung sounds are recorded and stored as digitized data. Algorithms are applied to the data producing an output indicative of the health of the animal. Another method determines effectiveness of antibiotics administered to animals based upon observed relationships between lung score categories obtained from auscultation. A comparison is made between sample populations of animals that receive different classifications of antibiotics, and this data is compared to lung score categories observed for each of the animals that received the antibiotics. A statistical analysis is conducted to confirm statistical differences in case fatality rates between lung score categories. Insignificant differences in mortality rates across a range of lung score categories indicates the particular antibiotic administered is not effective, whereas a reduced fatality rate associated with lower lung scores indicates a level of antibiotic effectiveness.
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Citations
6 Claims
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1. A method for determining effectiveness of an administered drug in treating a disease of a group of livestock using auscultation analysis, said method comprising:
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administering a first drug to a group of livestock; conducting auscultations by an electronic stethoscopic device communicating with a computer processor to record auscultated sounds from the group of livestock; determining, by said computer processor, a lung score corresponding to a respective level of severity of the disease for each livestock at the time of and based on the auscultations; recording, in said computer processor, the first drug administered to the group of livestock; recording, in said computer processor, fatalities for the group of livestock over a designated time period; conducting, by said computer processor, a statistical analysis to determine whether there is a statistical difference in fatality rates between lung score categories; analyzing, by said computer processor, the statistical analysis; automatically determining, by said computer processor, a numerical relationship between fatality rates as a function of lung scores to determine effectiveness of the first drug, said automatically determining step includes;
generating a graphical comparison of fatality rates versus lung score categories, said comparison including a predicted probability line of the fatality rates as a function of the lung scores;determining whether the first drug is effective or ineffective based on the slope of the predicted probability line, wherein the slope of the predicted probability line being positive indicates drug effectiveness and wherein the slope of said predicted probability line having a zero slope indicates drug ineffectiveness; and administering a second different drug to the group of animals when the first drug is ineffective, or administering the first drug to the group of livestock when the first drug is effective. - View Dependent Claims (2)
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3. A method for determining effectiveness of an administered drug in treating a disease of a group of livestock using auscultation analysis, said method comprising:
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administering a first drug to a group of livestock; conducting auscultations by an electronic stethoscopic device communicating with a computer processor to record auscultated sounds from the group of livestock; determining, by said computer processor, a lung score corresponding to a respective level of severity of the disease for each livestock at the time of and based on the auscultations; recording, in said computer processor, the first drug administered to the group of livestock; recording, in said computer processor, fatalities for the group of livestock over a designated time period; conducting, by said computer processor, an analysis to determine whether there is a difference in fatality rates between lung score categories; analyzing, by said computer processor, the statistical analysis; automatically determining, by said computer processor, a numerical relationship between fatality rates as a function of lung scores to determine effectiveness of the first drug, said automatically determining step includes;
generating a graphical comparison of fatality rates versus lung score categories, said comparison including a predicted probability line of the fatality rates as a function of the lung scores;determining whether the first drug is effective or ineffective based on the slope of the predicted probability line, wherein the slope of the predicted probability line being positive indicates drug effectiveness and wherein the slope of said predicted probability line having a zero slope indicates drug ineffectiveness; and administering a second different drug to the group of animals when the first drug is ineffective, or administering the first drug to the group of livestock when the first drug is effective. - View Dependent Claims (4, 5, 6)
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Specification