Systems for treating post-traumatic stress disorder
First Claim
1. A closed-loop therapy delivery system for treating post-traumatic stress disorder (PTSD) in a subject, the therapy delivery system comprising:
- a sensing component configured to detect at least one physiological parameter associated with PTSD;
a delivery component configured for implantation on or about a stellate ganglion of the sympathetic nervous system (SNS) to be in electrical communication with the stellate ganglion; and
a controller configured to automatically coordinate operation of the sensing and delivery components;
wherein the controller is programmed to deliver an electrical signal to the delivery component so that activity of the stellate ganglion of the SNS is continuously blocked to treat the PTSD without enhancing a symptom of PTSD.
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Abstract
One aspect of the present disclosure relates to a closed-loop therapy system for treating post-traumatic stress disorder (PTSD) in a subject. The therapy delivery system can include a sensing component, a delivery component, and a controller. The sensing component can be configured to detect at least one physiological parameter associated with PTSD. The delivery component can be configured for implantation on or about a ganglion of the sympathetic nervous system (SNS). The controller can be configured to automatically coordinate operation of the sensing and delivery components. The controller can also be configured to deliver an electrical signal to the delivery component so that activity of the ganglion of the SNS is substantially blocked without enhancing a symptom of PTSD.
13 Citations
12 Claims
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1. A closed-loop therapy delivery system for treating post-traumatic stress disorder (PTSD) in a subject, the therapy delivery system comprising:
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a sensing component configured to detect at least one physiological parameter associated with PTSD; a delivery component configured for implantation on or about a stellate ganglion of the sympathetic nervous system (SNS) to be in electrical communication with the stellate ganglion; and a controller configured to automatically coordinate operation of the sensing and delivery components; wherein the controller is programmed to deliver an electrical signal to the delivery component so that activity of the stellate ganglion of the SNS is continuously blocked to treat the PTSD without enhancing a symptom of PTSD. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for treating PTSD in a subject, the method comprising the steps of:
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placing a therapy delivery device into electrical communication with a stellate ganglion of the SNS; and activating the therapy delivery device to deliver an electrical signal to the stellate ganglion of the SNS so that activity of the stellate ganglion of the SNS is continuously blocked to treat the PTSD without enhancing a symptom of PTSD. - View Dependent Claims (8, 9, 10, 11, 12)
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Specification