Mitral heart valve replacement

• US 10,070,954 B2
• Filed: 03/22/2016
• Issued: 09/11/2018
• Est. Priority Date: 03/24/2015
• Status: Active Grant

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Inventors: Braido, Peter N., Fahim, Mina S., Benson, Thomas M., Dale, Theodore Paul, Para, Andrea N., Krans, Mark, Glimsdale, Mathias Charles
• Primary Examiner(s): Baria, Dinah
• Application Number:
  US15/076,854
• Publication Number:
  US 20160278922A1
• Time in Patent Office: 903 Days
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2469 with resilient valve members, e.g. conical spiral
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2230/0069 cylindrical

Abstract

A prosthetic heart valve having an inflow end and an outflow end includes a collapsible and expandable stent including a plurality of cells arranged in rows extending around a circumference of the stent, at least one of the rows forming a flared portion having a diameter that is larger than diameters of others of the rows. The stent further includes engaging arms disposed adjacent the outflow end and extending toward the inflow end, the engaging arms being configured to couple to heart tissue to anchor the stent. A collapsible and expandable valve assembly has a plurality of leaflets disposed within the stent.

Claims

1. A prosthetic heart valve having an inflow end and an outflow end, comprising:

a collapsible and expandable stent including a plurality of cells arranged in rows, each of the rows extending around a circumference of the stent, at least one of the rows forming a flared portion having a diameter that is larger than diameters of others of the rows, at least one of the rows including a plurality of cells having a first shape and a plurality of cells having a second shape different than the first shape, the stent further including engaging arms disposed adjacent the outflow end and extending toward the inflow end, the engaging arms being configured to couple to heart tissue to anchor the stent; and

a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets.

2. The prosthetic heart valve of claim 1, wherein at least one of the rows includes symmetric cells and asymmetric cells.

3. The prosthetic heart valve of claim 2, wherein the symmetric cells are substantially diamond shaped and the asymmetric cells comprise a curved portion.

4. The prosthetic heart valve of claim 1, wherein at least one row forming the flared portion includes cells having a dimension along the circumference of the stent that is larger than a dimension along the circumference of the stent of cells of other rows.

5. The prosthetic heart valve of claim 1, wherein each of the rows includes nine cells.

6. The prosthetic heart valve of claim 1, wherein each of the rows includes twelve cells.

7. The prosthetic heart valve of claim 1, wherein each of the engaging arms is nested within a respective one of the cells having the second shape.

8. The prosthetic heart valve of claim 1, wherein the engaging arms are positioned on the stent so that, in use, two engaging arms are arranged to couple to each native valve leaflet at a site of implantation.

9. The prosthetic heart valve of claim 1, wherein the flared portion forms an angle of between about 120 degrees and about 180 degrees with respect to a longitudinal axis of the stent.

10. The prosthetic heart valve of claim 1, further comprising a cuff disposed over at least two rows of the stent and a skirt disposed over at least one row of the stent.

11. The prosthetic heart valve of claim 10, wherein the cuff comprises three segments that are joined together at seams.

12. The prosthetic heart valve of claim 10, wherein the cuff is integrally formed from a single piece of material.

13. The prosthetic heart valve of claim 1, further comprising a radiopaque marker connected to at least one of the engaging arms.

14. The prosthetic heart valve of claim 1, wherein the stent further includes a plurality of horseshoes formed on one end of selected cells in at least two of the rows.

15. A prosthetic heart valve having an inflow end and an outflow end, comprising:

a collapsible and expandable stent including a plurality of cells arranged in rows, each of the rows extending around a circumference of the stent, the rows including a first row of cells having a first diameter and a second row of cells having a second diameter, the second diameter being larger than the first diameter, the first row including a plurality of cells having a first shape and a plurality of cells having a second shape different than the first shape the stent further including engaging arms nested within at least one of the plurality of cells having the second shape;

a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets;

an annular cuff disposed over cells of the first row of cells; and

an annular skirt disposed over cells of the second row of cells.

16. The prosthetic heart valve of claim 15, wherein the skirt includes a plurality of quadrilateral tabs with a triangular slit between each adjacent pair of tabs.

17. The prosthetic heart valve of claim 16, wherein the plurality of quadrilateral tabs includes nine tabs.

18. The prosthetic heart valve of claim 16, wherein the plurality of quadrilateral tabs includes a quadrilateral tab corresponding to each cell in the second row of cells.

19. The prosthetic heart valve of claim 15, wherein the skirt includes three segments that are sewn together.

20. The prosthetic heart valve of claim 15, wherein the skirt includes first wedges, second wedges, and a plurality of slits defined between the first wedges and the second wedges.