Devices for transferring fluid to or from a vial

• US 10,071,020 B2
• Filed: 07/21/2017
• Issued: 09/11/2018
• Est. Priority Date: 04/12/2006
• Status: Active Grant

• Current Assignee: ICU Medical Incorporated
• Original Assignee: ICU Medical Incorporated
• Inventors: Warren, Dee E., Lopez, Dan
• Primary Examiner(s): DEAK, LESLIE R
• Application Number:
  US15/656,970
• Publication Number:
  US 20170333288A1
• Time in Patent Office: 417 Days
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1412 Containers with closing means, e.g. caps
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2048 Connecting means
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2079 Filtering means
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2086 for fluid filtration
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 1/22 with means for metering the amount of fluid
• CPC Class Codes: A61J 2200/10 Coring prevention means, e.g. for plug or septum piecing members
• CPC Class Codes: A61J 2200/76 for fluid level
• CPC Class Codes: Y10T 137/0402 Cleaning, repairing, or assembling
• CPC Class Codes: Y10T 29/49826 Assembling or joining
• CPC Class Codes: Y10T 29/49885 with coating before or during assembling

Abstract

In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

Claims

1. A system for accessing medicinal fluid in a vial, the system comprising:

a connector configured to couple the system with the vial containing the medicinal fluid;

a medical connector interface configured to be releasably placed in fluid communication with a syringe;

an extractor channel configured to be in fluid communication with the medical connector interface and an extractor aperture, wherein the extractor aperture is configured to be inserted into the vial as a result of the connector being coupled with the vial, and wherein the extractor channel is configured to allow fluid to be transferred to and from the vial via the medical connector interface;

a reservoir comprising sterilized gas, wherein the system is configured to ensure that the sterilized gas remains contained in the system and sterile up through coupling of the system with the vial, and wherein the system is configured to regulate pressure within the vial using the sterilized gas as a result of the medicinal fluid being removed from the vial via the extractor channel without permitting ambient air to be introduced into the vial; and

a regulator channel configured to be in fluid communication with the reservoir and a regulator aperture, wherein the regulator aperture is configured to be inserted into the vial, and wherein the regulator channel is configured to allow the sterilized gas to move between the reservoir and the interior of the vial as a result of the system being coupled with the vial and at the same time that medicinal fluid is being introduced into or removed from the vial.

2. The system of claim 1, wherein the reservoir is configured to decrease in volume as a result of a volume of medicinal fluid being withdrawn from the vial, wherein the decrease in volume of the reservoir corresponds to the volume of medicinal fluid withdrawn from the vial.

3. The system of claim 1, wherein the reservoir is configured to maintain a substantially constant pressure within the vial by supplying sterilized gas to the vial during withdrawal of medicinal fluid from the vial.

4. The system of claim 1, wherein the reservoir is configured to decrease in volume as medicinal fluid is removed from the vial, thereby regulating pressure within the vial.

5. The system of claim 1, wherein the reservoir is circularly symmetric.

6. The system of claim 1, wherein the reservoir is symmetric about a latitudinal plane passing through a center of the reservoir.

7. The system of claim 1, wherein the reservoir comprises a volume of gas equal to or greater than the volume of medicinal fluid contained in the vial that can be transferred into the vial while regulating pressure within the vial.

8. The system of claim 1, wherein the reservoir comprises a longitudinal axis parallel to a longitudinal axis of the extractor channel.

9. The system of claim 1, further comprising a casing member that defines a cavity for housing the reservoir, wherein the casing member comprises the medical connector interface.

10. The system of claim 1, wherein the reservoir has a height of at least 2 inches.

11. The system of claim 1, wherein the reservoir has a width of at least 0.8 inches.

12. The system of claim 1, further comprising a barrier configured to maintain sterility of the gas in the reservoir up through coupling of the system with the vial.

13. The system of claim 1, further comprising a medical connector interface configured to couple the system with a medical device that is in fluid communication with the extractor channel as a result of the medical device being coupled to the medical connector interface.

14. The system of claim 1, further comprising a medical connector interface in fluid communication with the extractor channel, wherein the medical connector interface is configured to interface with a syringe that has no exposed needle.