Method for preparing 3,6-anhydro-L-galactose, and use thereof

• US 10,071,041 B2
• Filed: 08/29/2017
• Issued: 09/11/2018
• Est. Priority Date: 01/18/2012
• Status: Active Grant

• Current Assignee: Korea University Research and Business Foundation
• Original Assignee: Korea University Research and Business Foundation
• Inventors: Kim, Kyoung Heon, Choi, In Geol, Kang, Nam Joo, Yun, Eun Ju, Lee, Sae Young, Kim, Ji Hye, Kim, Young Ah, Kim, Bo Bae, Baek, Eun Ji
• Primary Examiner(s): McIntosh, III, Traviss C
• Application Number:
  US15/689,840
• Publication Number:
  US 20170360671A1
• Time in Patent Office: 378 Days
• Field of Search: None
• CPC Class Codes: A61K 31/7004 Monosaccharides having only carbon, hydrogen and oxygen atoms
• CPC Class Codes: A61K 8/60 Sugars; Derivatives thereof
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/007 Preparations for dry skin
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin
• CPC Class Codes: C07H 1/08 from natural products
• CPC Class Codes: C07H 3/10 Anhydrosugars, e.g. epoxides
• CPC Class Codes: C12P 19/02 Monosaccharides 2-ketogulonic acid C12P7/60
• CPC Class Codes: C12P 19/14 produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase , e.g. by cellulase, hemicellulase
• CPC Class Codes: C12Y 302/01 Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)

Abstract

The present invention relates to a method for preparing 3,6-anhydro-L-galactose, and use thereof. More specifically, 3,6-anhydro-L-galactose, which is a monosaccharide constituting agar, is produced in a high yield through chemical and enzymatic methods, and the physiological activities thereof such as whitening, moisturizing, antioxidant, anti-inflammatory activities and the like are displayed, thereby enabling industrial use thereof.

Claims

1. A method of whitening a skin, comprising administering an effective amount of 3,6-anhydro-L-galactose to a subject in need thereof.

2. The method of claim 1, wherein said administering includes applying 3,6-anhydro-L-galactose onto the skin.