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Reperfusion protection in resuscitation

  • US 10,071,218 B2
  • Filed: 10/29/2014
  • Issued: 09/11/2018
  • Est. Priority Date: 01/24/2006
  • Status: Active Grant
First Claim
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1. A medical system comprising:

  • at least one sensor configured to perform near infrared spectroscopy (NIRS), and to generate a signal representing a pH of tissues of a patient; and

    a processor communicably coupled to the at least one sensor, the processor configured to;

    receive the signal; and

    generate an instruction configured to result in a ventilator adjusting a partial pressure of CO2 in a gas mixture delivered to the patient to one or more partial pressures high enough to slow expiration of CO2 from the patient'"'"'s lungs and thereby maintain an increased PCO2 in tissues of the patient for a period of time following return of spontaneous circulation (ROSC),wherein the instruction is configured to result in the ventilator adjusting the partial pressure of the CO2 in the gas mixture so as to maintain the pH at a constant level for a first portion of the period of time following ROSC.

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