System and methods for clinical effects mapping for directional stimulation leads

• US 10,071,249 B2
• Filed: 10/04/2016
• Issued: 09/11/2018
• Est. Priority Date: 10/09/2015
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Zottola, Dennis
• Primary Examiner(s): MALAMUD, DEBORAH LESLIE
• Application Number:
  US15/285,374
• Publication Number:
  US 20170100593A1
• Time in Patent Office: 707 Days
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36182 Direction of the electrical field, e.g. with sleeve around stimulating electrode
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

A method includes displaying, on a display coupled to a computer processor, a two-dimensional representation of an arrangement of electrodes of a lead having one or more segmented electrodes; displaying, by the computer processor and on the display, a three-dimensional clinical effects map with two of the dimensions of the clinical effects map corresponding to the two-dimensional representation of the arrangement of the electrode and a third dimension corresponding to a stimulation parameter; and displaying, by the computer processor and on the display, at least one marking on the clinical effects map. Each marking represents a stimulation instance and is displayed at a position corresponding to the electrode used for stimulation in the stimulation instance and a value of the stimulation parameter used for stimulation in the stimulation instance. Each marking has a graphical characteristic representing a therapeutic effect or a side-effect resulting from the stimulation instance.

Claims

1. A computer-implemented method comprising:

displaying, by a computer processor and on a display coupled to the computer processor, a two-dimensional representation of an arrangement of electrodes of a lead having one or more segmented electrodes;

displaying, by the computer processor and on the display, a three-dimensional clinical effects map having a first axis, a second axis, and a third axis, wherein the first axis is perpendicular to the second and third axes, wherein the first axis and second axis of the clinical effects map correspond to the two-dimensional representation of the arrangement of the electrodes and the third axis represents one of a plurality of stimulation parameters with positions along the third axis corresponding to numerical values of the one of the stimulation parameters; and

displaying, by the computer processor and on the display, a plurality of markings on the clinical effects map, wherein each of the markings represents a stimulation instance and is displayed at a position with coordinates along the first axis and second axis corresponding to the electrode used for stimulation in the stimulation instance and a coordinate along the third axis corresponding to the numerical value of the one of the stimulation parameters used for stimulation in the stimulation instance, wherein each marking has a graphical characteristic representing a therapeutic effect or a side-effect resulting from the stimulation instance.

2. The method of claim 1, further comprising

selecting a one of the markings;

and

delivering, by the computer processor, electrical stimulation parameters corresponding to the one of the markings to an electrical stimulation system for delivery of electrical stimulation to a patient using the stimulation parameters.

3. The method of claim 2, wherein delivering electrical stimulation parameters comprises delivering, to the electrical stimulation system, an identification of the electrode associated with the one of the markings and the value of the stimulation parameter associated with the one of the markings.

4. The method of claim 1, wherein the stimulation parameter to which the third axis corresponds is stimulation amplitude.

5. The method of claim 1, wherein the graphical characteristic is selected from color or cross-hatching.

6. The method of claim 1, wherein displaying the plurality of markings comprises displaying the markings with a further graphical characteristic representing a score or rating of the therapeutic effect or the side-effect resulting from the stimulation instance.

7. The method of claim 6, wherein the further graphical characteristic is selected from color, shade, intensity, saturation, cross-hatching, or texture.

8. The method of claim 1, wherein displaying the plurality of markings comprises displaying at least one of the markings with a first graphical characteristic representing a first therapeutic effect resulting from the stimulation instance and a second graphical characteristic representing a first side-effect resulting from the stimulation instance.

9. The method of claim 8, wherein the first graphical characteristic is associated with a surface of the marking and the second graphical characteristic is associated with a perimeter ring of the marking.

10. The method of claim 1, wherein displaying the plurality of markings comprises displaying a plurality of the markings associated with one of the electrodes of the lead in a column.

11. The method of claim 1, further comprising selecting a one of the electrodes in the two-dimensional representation and highlighting all of the markings associated with the selected electrode.

12. The method of claim 1, further comprising displaying, by the computer processor and on the display, a three-dimensional representation of the arrangement of the electrodes of the lead separate from, and simultaneously with, the clinical effects map and two-dimensional representation.

13. The method of claim 12, further comprising selecting a one of the electrodes in the three-dimensional representation and highlighting all of the markings associated with the selected electrode and highlighting the selected electrode in the two-dimensional representation.

14. The method of claim 12, further comprising selecting a one of the electrodes in the two-dimensional representation and highlighting all of the markings associated with the selected electrode and highlighting the selected electrode in the three-dimensional representation.

15. The method of claim 1, further comprising selecting a one of the markings and highlighting the selected one of the markings and the electrode, in the two-dimensional representation, associated with the selected one of the markings.

16. A system for mapping clinical effects of electrical stimulation,

the system comprising:

a display; and

a computer processor coupled to the display and configured and arranged to perform the following actions;

display, on the display, a two-dimensional representation of an arrangement of electrodes of a lead having one or more segmented electrodes;

display, on the display, a three-dimensional clinical effects map having a first axis, a second axis, and a third axis, wherein the first axis is perpendicular to the second and third axes, wherein the first axis and second axis of the clinical effects map correspond to the two-dimensional representation of the arrangement of the electrodes and the third axis represents one of a plurality of stimulation parameters with positions along the third axis corresponding to numerical values of the one of the stimulation parameters; and

display, on the display, a plurality of markings on the clinical effects map, wherein each of the markings represents a stimulation instance and is displayed at a position with coordinates along the first axis and second axis corresponding to the electrode used for stimulation in the stimulation instance and a coordinate along the third axis corresponding to the numerical value of the one of the stimulation parameters used for stimulation in the stimulation instance, wherein each marking has a graphical characteristic representing a therapeutic effect or a side-effect resulting from the stimulation instance.

17. The system of claim 16, wherein the actions further comprise

receive a selection of a one of the markings;

and

transmit electrical stimulation parameters corresponding to the one of the markings to an electrical stimulation system for delivery of electrical stimulation to a patient using the stimulation parameters.

18. The system of claim 16, wherein the actions further comprise

display, on the display, a three-dimensional representation of the arrangement of the electrodes of the lead separate from, and simultaneously with, the clinical effects map and two-dimensional representation.

19. A non-transitory computer-readable medium having processor-executable instructions for mapping clinical effects of electrical stimulation, the processor-executable instructions when installed onto a device enable the device to perform actions, including:

display, on a display coupled to the computer processor, a two-dimensional representation of an arrangement of electrodes of a lead having one or more segmented electrodes;

display, on the display, a three-dimensional clinical effects map having a first axis, a second axis, and a third axis, wherein the first axis is perpendicular to the second and third axes, wherein the first axis and second axis of the clinical effects map correspond to the two-dimensional representation of the arrangement of the electrodes and the third axis represents one of a plurality of stimulation parameters with positions along the third axis corresponding to numerical values of the one of the stimulation parameters; and

display, on the display, a plurality of markings on the clinical effects map, wherein each of the markings represents a stimulation instance and is displayed at a position with coordinates along the first axis and second axis corresponding to the electrode used for stimulation in the stimulation instance and a coordinate along the third axis corresponding to the numerical value of the one of the stimulation parameters used for stimulation in the stimulation instance, wherein each marking has a graphical characteristic representing a therapeutic effect or a side-effect resulting from the stimulation instance.

20. The non-transitory computer-readable medium of claim 19, wherein the actions further comprise

receive a selection of a one of the markings;

and

transmit electrical stimulation parameters corresponding to the one of the markings to an electrical stimulation system for delivery of electrical stimulation to a patient using the stimulation parameters.