Sample analyzing apparatus, disease monitoring system, and method for managing multiple disease determination data in a sample analyzing apparatus

• US 10,073,080 B2
• Filed: 07/15/2014
• Issued: 09/11/2018
• Est. Priority Date: 07/23/2013
• Status: Active Grant

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Toyoda, Akio, Akamatsu, Shinjirou
• Primary Examiner(s): Lapage, Michael P
• Application Number:
  US14/331,386
• Publication Number:
  US 20150029508A1
• Time in Patent Office: 1,519 Days
• CPC Class Codes: G01N 15/01 specially adapted for biological cells, e.g. blood cells investigating sedimentation of particle suspensions in blood G01N15/05
• CPC Class Codes: G01N 15/05 in blood
• CPC Class Codes: G01N 15/1434 Optical arrangements
• CPC Class Codes: G01N 15/1459 the analysis being performed on a sample stream
• CPC Class Codes: G01N 2015/012 Red blood cells
• CPC Class Codes: G01N 2015/016 White blood cells
• CPC Class Codes: G01N 2015/018 Platelets
• CPC Class Codes: G01N 2015/055 for hematocrite determination
• CPC Class Codes: G01N 2035/00881 network configurations
• CPC Class Codes: G01N 2035/009 alarms, e.g. audible
• CPC Class Codes: G01N 2035/0091 GUI [graphical user interfaces]
• CPC Class Codes: G01N 21/53 within a flowing fluid, e.g. smoke
• CPC Class Codes: G01N 21/6458 Fluorescence microscopy fluorescence microscopes per se G02B21/0076 and G02B21/16
• CPC Class Codes: G01N 33/4915 using flow cells flow cytometry G01N15/14
• CPC Class Codes: G01N 33/492 Determining multiple analytes
• CPC Class Codes: G01N 35/00871 Communications between instruments or with remote terminals
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

A sample analyzing apparatus comprising a measurement unit configured to measure samples obtained from subjects, an obtaining unit configured to obtain the presence or absence of a disease regarding each sample, a memory in which a measurement result obtained by the measurement unit and the presence or absence of the disease obtained by the obtaining unit are stored in association with the sample, and a communication unit configured to transmit disease information based on the presence or absence of the disease stored in the memory to a receiving apparatus installed in an external facility.

Claims

1. A sample analyzing apparatus comprising:

a detector that measures blood cells in a sample obtained from a subject so as to count the blood cells to produce a measurement result comprising a count result of the blood cells for the sample;

an input unit that receives a manual input of one or more externally obtained diagnosis results of a presence or absence of a disease for the sample;

a memory in which the count result of the blood cells for the sample, and the manual input of one or more externally obtained diagnosis results for the sample, are both stored in association with the sample;

a communication transmitter that transmits disease information based on the presence or absence of the disease stored in the memory in association with the sample, over a communication link to a receiving apparatus installed in an external facility; and

a processor coupled to the detector, the memory, and the communication transmitter, the processor executing a computer program stored in the memory, the processor configured by the computer program to perform operations to;

control and to receive signals from the detector and to process the received signals; and

compare the manually inputted one or more externally obtained diagnosis results of the presence or absence of the disease with the count result obtained by the detector.

2. The sample analyzing apparatus of claim 1, wherein

the processor is further configured by the computer program to perform operations to receive the manual input of the one or more externally obtained diagnosis results of the presence or absence of the disease.

3. The sample analyzing apparatus of claim 1, wherein

the processor is further configured by the computer program to perform operations to determine the presence or absence of the disease regarding the sample, based on the measurement result obtained by the detector.

4. The sample analyzing apparatus of claim 3, wherein

the processor is further configured to perform operations to

when having determined that the inputted one or more manual determinations of the presence or absence of the disease is incorrect, cause a predetermined alarm.

5. The sample analyzing apparatus of claim 1, wherein

the communication transmitter transmits the disease information to the receiving apparatus, every time a predetermined period has elapsed.

6. The sample analyzing apparatus of claim 1, wherein

when a number of pieces of the disease information that have not yet been transmitted to the receiving apparatus has reached a predetermined number, the communication transmitter transmits, to the receiving apparatus, the pieces of the disease information that have not yet been transmitted.

7. The sample analyzing apparatus of claim 1, wherein

the communication transmitter transmits, along with the disease information, location information regarding a location where the sample analyzing apparatus is installed, to the receiving apparatus.

8. The sample analyzing apparatus of claim 1, wherein

the disease is HIV/AIDS, tuberculosis, or malaria.

9. The sample analyzing apparatus of claim 1, wherein

the communication transmitter performs wireless communication with a communication network to which the receiving apparatus is connected.

10. The sample analyzing apparatus of claim 1, further comprising

a display coupled to the processor, wherein

the processor is further configured to perform operations to cause the display to display the measurement result along with the presence or absence of the disease.

11. The sample analyzing apparatus of claim 1, wherein

the communication transmitter transmits the count result of the count of the blood cells along with the disease information, to the receiving apparatus installed in the external facility.

12. A disease monitoring system comprising:

a plurality of the sample analyzing apparatuses of claim 1; and

a plurality of the receiving apparatuses.

13. The disease monitoring system of claim 12, wherein

each of the plurality of the receiving apparatuses comprises a display, and

each of the plurality of the receiving apparatuses comprises a processor executing a stored computer program, the processor configured by the computer program to perform operations to

calculate a total of the number of positive samples or to calculate a positive rate regarding the disease based on the disease information received from the sample analyzing apparatus, and

cause the display to display the number of positive samples or the positive rate on the display.

14. The disease monitoring system of claim 13, wherein

the processor is further configured to perform an operation to provide an alarm when the number of positive samples or the positive rate is greater than or equal to a predetermined value.

15. The disease monitoring system of claim 13, wherein

the processor is further configured to perform an operation to provide an alarm when the number of positive samples is greater than or equal to a predetermined value and the positive rate is greater than or equal to a predetermined value.

16. The disease monitoring system of claim 13, wherein

the processor is further configured to perform an operation to calculate a total of the number of positive samples or to calculates the positive rate, for each district where the respective one of the plurality of sample analyzing apparatuses is located.

17. The disease monitoring system of claim 16, wherein

the processor is further configured to perform an operation to cause the number of positive samples or the positive rate to be displayed on the display in combination with a map.

18. The disease monitoring system of claim 12, wherein

the processor of each of the plurality of sample analyzing apparatuses is further configured to perform operations to transmit the disease information to a respective one of the plurality of receiving apparatuses when determination of the disease regarding the sample is positive, and when determination of the disease regarding the sample is negative.

19. The disease monitoring system of claim 12, wherein

the processor of each of the plurality of sample analyzing apparatuses is further configured to perform operations to transmit the disease information and information indicating one of:

a sex and an age of each subject from whom a sample has been obtained to a respective one of the plurality of receiving apparatuses.

20. The sample analyzing apparatus of claim 1, wherein the processor is further configured by the computer program to perform operations to determine whether the manually inputted one or more externally obtained diagnosis results of the presence or absence of the disease is incorrect based on the measurement result obtained by the detector such that:

when a value of the measurement result obtained by the detector is outside of an expected range of values when a presence of the disease is determined, the manually inputted one or more externally obtained diagnosis results of the presence of the disease is determined to be incorrect; and

when a value of the measurement result obtained by the detector is outside of an expected range of values when an absence of the disease is determined, the manually inputted one or more externally obtained diagnosis results of the absence of the disease is determined to be incorrect.

21. A method for managing data of a sample analyzing apparatus comprising a processor executing a computer program, a communication transmitter, a detector that measures a sample, an input unit, and a memory, the method comprising:

measuring, by the detector, blood cells in the sample so as to count the blood cells to produce a measurement result comprising a count result of the blood cells for the sample;

obtaining, by the processor from the input unit, a manual input of one or more externally obtained diagnosis results of a presence or absence of a disease for the sample;

storing, in the memory, both the count result of measuring the blood cells, and the one or more manual inputs of the one or more respective externally obtained diagnosis results in association with the sample;

compare the manually inputted one or more externally obtained diagnosis results of the presence or absence of the disease with the count result obtained by the detector; and

transmitting, by the communication transmitter, disease information based on the presence or absence of the disease to a receiving apparatus installed in an external facility.