Method and system for image processing to determine patient-specific blood flow characteristics
First Claim
1. A method for image analysis to perform vascular assessment during a session of vascular catheterization of a subject, the method comprising:
- receiving a plurality of angiographic images imaging a portion of the vasculature of the subject, wherein the portion of the vasculature comprises a stenosis, and wherein the plurality of angiographic images are obtained during the session;
producing, by automatic processing of the plurality of angiographic images, a first vascular tree model modeling the portion of the vasculature;
determining automatically a second vascular tree model by modifying the first vascular tree model to model an opening of the stenosis;
performing a simulation of a blood flow characteristic through the first vascular tree model and a simulation of the blood flow characteristic through the second vascular tree model reflecting the opening of the stenosis;
determining automatically, a percentage change in the blood flow characteristic caused by opening the stenosis, using the simulation of the blood flow characteristic through the first vascular tree model and the simulation of the blood flow characteristic through the second vascular tree model reflecting opening of the stenosis; and
identifying characteristics of a treatment option based on the determined percentage change in the blood flow characteristic;
wherein the receiving, producing, determining, and identifying are performed while the subject remains in the session and catheterized.
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Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient'"'"'s heart, and create a three-dimensional model representing at least a portion of the patient'"'"'s heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient'"'"'s heart and determine a fractional flow reserve within the patient'"'"'s heart based on the three-dimensional model and the physics-based model.
290 Citations
15 Claims
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1. A method for image analysis to perform vascular assessment during a session of vascular catheterization of a subject, the method comprising:
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receiving a plurality of angiographic images imaging a portion of the vasculature of the subject, wherein the portion of the vasculature comprises a stenosis, and wherein the plurality of angiographic images are obtained during the session; producing, by automatic processing of the plurality of angiographic images, a first vascular tree model modeling the portion of the vasculature; determining automatically a second vascular tree model by modifying the first vascular tree model to model an opening of the stenosis; performing a simulation of a blood flow characteristic through the first vascular tree model and a simulation of the blood flow characteristic through the second vascular tree model reflecting the opening of the stenosis; determining automatically, a percentage change in the blood flow characteristic caused by opening the stenosis, using the simulation of the blood flow characteristic through the first vascular tree model and the simulation of the blood flow characteristic through the second vascular tree model reflecting opening of the stenosis; and identifying characteristics of a treatment option based on the determined percentage change in the blood flow characteristic; wherein the receiving, producing, determining, and identifying are performed while the subject remains in the session and catheterized. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system for image analysis to perform vascular assessment during a session of vascular catheterization of a subject, the system comprising:
a computer functionally connected to receive from an angiographic imaging device a plurality of images captured during the session, the plurality of images imaging a portion of a vasculature of the subject comprising a stenosis; wherein the computer is further configured to calculate a first vascular tree model from the plurality of images while the subject remains in the session and catheterized; wherein the computer is further configured to determine a second vascular tree model by modifying the first vascular tree model to model an opening of the stenosis; wherein the computer is configured to perform a simulation of a blood flow characteristic through the first vascular tree model and a simulation of the blood flow characteristic through the second vascular tree model reflecting the opening of the stenosis; wherein the computer is configured to determine percentage change in the blood flow characteristic caused by opening of the stenosis, using the simulation of the blood flow characteristic through the first vascular tree model and the simulation of the blood flow characteristic through the second vascular tree model reflecting opening of the stenosis, while the subject remains in the session and catheterized; and wherein the computer is also configured to identify and display one or more of the first vascular tree model, the second vascular tree model, the determined percentage change in the blood flow characteristic, or characteristics of a treatment option based on the determined percentage change in the blood flow characteristic. - View Dependent Claims (15)
Specification