Systems and methods for delivery of peptides
First Claim
1. A composition, comprising:
- a carrier comprising thyrotropin-releasing hormone (TRH) and lecithin entrapping molecular nitric oxide, wherein the composition is stable at room temperature.
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Abstract
The present invention generally relates to compositions and methods for topical or transdermal delivery. The compositions can be used in a variety of applications. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. The composition can also be applied to a mucosal surface in some instances. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.
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20 Claims
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1. A composition, comprising:
a carrier comprising thyrotropin-releasing hormone (TRH) and lecithin entrapping molecular nitric oxide, wherein the composition is stable at room temperature. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A composition, comprising:
a carrier comprising thyrotropin-releasing hormone (TRH) and lecithin entrapping molecular nitric oxide, wherein the first phase comprises no more than about 250 ppm of water by weight of the composition. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
Specification