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Antibodies recognizing α-synuclein

  • US 10,081,674 B2
  • Filed: 02/10/2017
  • Issued: 09/25/2018
  • Est. Priority Date: 10/08/2012
  • Status: Expired due to Fees
First Claim
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1. A method of treating, reducing risk, lessening severity or delaying onset of a Lewy body disease in a patient having or at risk of a Lewy body disease comprising administering to the patient an effective regime of an antibody comprising three light chain CDRs and three heavy chain CDRs of monoclonal antibody 5C1, wherein 5C1 is a mouse antibody characterized by a heavy chain variable region having an amino acid sequence comprising SEQ ID NO:

  • 9 and light chain variable region having an amino acid sequence comprising SEQ ID NO;

    24 and thereby treating, reducing risk, lessening severity or delaying onset of the disease.

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