Optical measuring device for cardiovascular diagnostics
First Claim
1. An optical measuring device for measuring cardiovascular properties, comprising:
- a flexible substrate configured as a patch to wrap around a first region and a second region of a subject, the first region movable with respect with the second region;
a first optical sensor attached to an inner surface of the flexible substrate and comprising a first light source, a first light detector, and a first transmit light guide coupled to the first light source, the first transmit light guide being configured to direct light from the first light source as a first sheet of light towards an artery in the first region, the first light detector being configured to receive first backscattered light and generate a first output based on the received first backscattered light, wherein the first backscattered light is light from the first sheet of light that is reflected from the artery and tissues surrounding the artery in the first region; and
a second optical sensor attached to the inner surface of the flexible substrate comprising a second light detector, a second light source and a second transmit light guide coupled to the second light source, the second transmit light guide being configured to direct light from the second light source as a second sheet of light towards the artery in the second region, the second light detector being configured to receive second backscattered light and generate a second output based on the received second backscattered light, wherein the second backscattered light is light from the second sheet of light that is reflected from the artery and tissues surrounding the artery in the second region.
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Abstract
An optical sensor and a method of using the optical sensor in an optical measuring device that measures cardiovascular properties and compensates for movement artifacts by directing a sheet of light towards an artery. The optical sensor may include one or more light sources, one or more transmit light guides coupled to the one or more light sources and configured to direct light from the one or more light sources as a sheet of light towards an artery, such that the cross-sectional profile of the sheet of light may have a length transverse to a longitudinal direction of the artery that is longer than the diameter of the artery. The optical sensor may include one or more light detectors configured to receive backscattered light and generate an output based on the received backscattered light that is a reflection of the sheet of light from the artery and surrounding tissues.
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Citations
32 Claims
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1. An optical measuring device for measuring cardiovascular properties, comprising:
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a flexible substrate configured as a patch to wrap around a first region and a second region of a subject, the first region movable with respect with the second region; a first optical sensor attached to an inner surface of the flexible substrate and comprising a first light source, a first light detector, and a first transmit light guide coupled to the first light source, the first transmit light guide being configured to direct light from the first light source as a first sheet of light towards an artery in the first region, the first light detector being configured to receive first backscattered light and generate a first output based on the received first backscattered light, wherein the first backscattered light is light from the first sheet of light that is reflected from the artery and tissues surrounding the artery in the first region; and a second optical sensor attached to the inner surface of the flexible substrate comprising a second light detector, a second light source and a second transmit light guide coupled to the second light source, the second transmit light guide being configured to direct light from the second light source as a second sheet of light towards the artery in the second region, the second light detector being configured to receive second backscattered light and generate a second output based on the received second backscattered light, wherein the second backscattered light is light from the second sheet of light that is reflected from the artery and tissues surrounding the artery in the second region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of measuring cardiovascular properties using an optical measuring device applied to a subject, comprising:
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directing, using a first light guide attached to an inner surface of a flexible substrate, a first sheet of light from a first light source also attached to the inner surface of the flexible substrate towards an artery in a first region of the subject, the flexible substrate being wrapped around the first region and a second region of the subject, the first region being movable with respect to the second region; directing, using a second light guide attached to the inner surface of the flexible substrate, a second sheet of light from a second light source also attached to the inner surface of the flexible substrate towards the artery in the second region of the subject; receiving, using a first light detector attached to the inner surface of the flexible substrate, first backscattered light that is light from the first sheet of light reflected from the artery and tissues surrounding the artery in the first region; receiving, using a second light detector attached to the inner surface of the flexible substrate, second backscattered light that is light from the second sheet of light reflected from the artery and tissues surrounding the artery in the second region; and generating an output based on the first backscattered light received by the first light detector and the second backscattered light received by the second light detector. - View Dependent Claims (21, 22, 23, 24, 25)
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26. An optical measuring device for measuring cardiovascular properties, comprising:
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means for wrapping around a first region and a second region of a subject, the second region being movable with respect to the first region; means for directing a first sheet of light towards an artery in the first region of the subject; means for directing a second sheet of light towards the artery in a second region of the subject; means for receiving first backscattered light that is light from the first sheet of light reflected from the artery and tissues surrounding the artery in the first region; means for receiving second backscattered light that is light from the second sheet of light reflected from the artery and tissues surrounding the artery in the second region; and means for generating an output based on the received first backscattered light and the received second backscattered light, wherein the means for directing the first sheet of light, the means for directing the second sheet of light, the means for receiving the first backscattered light, and the means for receiving the second backscatter light are attached to the means for wrapping around the first region and the second region. - View Dependent Claims (27, 28, 29)
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30. An optical measuring device for measuring cardiovascular properties, comprising:
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a flexible substrate configured as a patch to wrap around a first region and a second region of a subject, the first region movable with respect with the second region; a first optical sensor attached to an inner surface of the flexible substrate and comprising a first light source, a first light detector, and a first transmit light guide coupled to the first light source, the first transmit light guide being configured to direct light from the first light source as a first sheet of light towards an artery in the first region, the first light detector being configured to receive first backscattered light and generate a first output based on the received first backscattered light, wherein the first backscattered light is light from the first sheet of light that is reflected from the artery and tissues surrounding the artery in the first region; a second optical sensor attached to the inner surface of the flexible substrate comprising a second light detector, a second light source and a second transmit light guide coupled to the second light source, the second transmit light guide being configured to direct light from the second light source as a second sheet of light towards the artery in the second region, the second light detector being configured to receive second backscattered light and generate a second output based on the received second backscattered light, wherein the second backscattered light is light from the second sheet of light that is reflected from the artery and tissues surrounding the artery in the second region; and a processor coupled to the first optical sensor and the second optical sensor and configured to determine one or more cardiovascular properties based on outputs from the first optical sensor and the second optical sensor. - View Dependent Claims (31, 32)
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Specification