Medical system for mapping cardiac tissue

• US 10,085,659 B2
• Filed: 10/02/2015
• Issued: 10/02/2018
• Est. Priority Date: 10/03/2014
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Laughner, Jacob I., Ricci, Carlos Alberto, Kovtun, Vladimir V., Shome, Shibaji, Thakur, Pramodsingh H., Shuros, Allan C., Stalsberg, Kevin J.
• Primary Examiner(s): WEHRHEIM, LINDSEY GAIL
• Application Number:
  US14/874,097
• Publication Number:
  US 20160183810A1
• Time in Patent Office: 1,096 Days
• CPC Class Codes: A61B 2505/05 Surgical care
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/347 Detecting the frequency distribution of signals
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/367 Electrophysiological study [EPS], e.g. electrical activation mapping or electro-anatomical mapping
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/7253 characterised by using transforms

Abstract

Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a catheter shaft. The catheter shaft includes a plurality of electrodes including a first and a second electrode. The system also includes a processor. The processor is capable of collecting a first signal corresponding to a first electrode over a time period and generating a first time-frequency distribution corresponding to the first signal. The first time-frequency distribution includes a first dominant frequency value representation occurring at one or more first base frequencies. The processor is also capable of applying a filter to the first signal or derivatives thereof to determine whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or two or more first dominant frequency values at two or more base frequencies.

Claims

1. A system for mapping the electrical activity of the heart, the system comprising:

a catheter shaft, wherein a plurality of electrodes is coupled thereto, and wherein the plurality of electrodes includes a first electrode and a second electrode;

a processor coupled to the first electrode and the second electrode, the processor configured to;

collect a first signal from the first electrode over a time period;

generate a first time-frequency distribution corresponding to the first signal, wherein the first time-frequency distribution includes a first dominant frequency value representation occurring at one or more first base frequencies; and

apply a filter to at least one of the first signal and a derivative of the first signal to determine whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or more than one first dominant frequency values at more than one base frequencies; and

generate a visual display of at least one of the filtered first signal and the filtered derivative of the first signal indicating whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or more than one first dominant frequency values at more than one base frequencies.

2. The system of claim 1, wherein the processor is further configured to:

collect a second signal from the second electrode over the time period;

generate a second time-frequency distribution corresponding to the second signal, wherein the second time-frequency distribution includes a second dominant frequency value representation, wherein the second dominant frequency value representation includes one or more second dominant frequency values occurring at one or more second base frequencies; and

determine an attraction point, wherein the attraction point is defined when the one or more first dominant frequency values substantially relate to the one or more second dominant frequency values.

3. The system of claim 2, wherein the processor is further configured to apply the filter to at least one of:

the second signal, a derivative of the second signal, and the attraction point.

4. The system of claim 3, wherein to apply the filter to at least one of:

the first signal, a derivative of the first, signal, the second signal, and a derivative of the second signal, the processor is configured to apply the filter prior to determining the attraction point.

5. The system of claim 3, wherein applying the filter to the first signal or derivatives thereof, to the second signal or derivatives thereof or to both signals or derivatives thereof includes applying the filter after determining the attraction point.

6. The system of claim 1, wherein to generate the first time-frequency distribution, the processor utilizes at least one of:

a Fourier transform, a Short-Time Fourier transform, and a Wavelet transform.

7. The system of claim 1, wherein to generate the time-frequency distribution, the processor is configured to generate a spectrogram of the first signal.

8. The system of claim 1, wherein to apply the filter to at least one of the first signal and a derivative of the first signal, the processor utilizes at least one of:

one or more harmonic components of the first signal and a derivative of the one or more harmonic components.

9. The system of claim 8, wherein to apply the filter to at least one of the first signal and a derivative of the first signal, the processor is configured to apply a comb filter to at least one of the first signal and a derivative of the first signal.

10. The system of claim 8, wherein to utilize at least one of one or more harmonic components of the first signal and a derivative of the one or more harmonic components, the processor is configured to identify frequency values at integer multiples of the one or more base frequencies, wherein the frequency values corresponding to the integer multiples are added to the one or more base frequency values.

11. The system of claim 1, wherein the processor is further configured to generate a visual display, wherein the visual display includes displaying at least one visual indicator, and wherein the visual indicator corresponds to the first and/or second signal or derivative thereof.

12. The system of claim 11, wherein to generate the visual display, the processor is configured to generate a display of at least one sinusoid corresponding to the one or more first and/or second base frequencies.

13. The system of claim 11, wherein to generate the visual display, the processor is configured to generate a display of a phase map.

14. The system of claim 11, wherein the visual indicator is a color, texture or both.

15. A method for mapping the electrical activity of the heart, the method comprising:

collecting a first signal corresponding to a first electrode coupled to a catheter over a time period;

collecting a second signal corresponding to a second electrode coupled to the catheter over the time period;

generating a first time-frequency distribution corresponding to the first signal, wherein the first time-frequency distribution includes a first dominant frequency value representation occurring at one or more first base frequencies;

generating a second time-frequency distribution corresponding to the second signal, wherein the second time-frequency distribution includes a second dominant frequency value representation, wherein the second dominant frequency value representation includes one or more second dominant frequency values occurring at one or more second base frequencies;

applying a filter to the first signal or derivatives thereof to determine whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or more than one first dominant frequency values at more than one base frequencies;

determining an attraction point, wherein the attraction point is defined when the one or more first dominant frequency values substantially relate to the one or more second dominant frequency values; and

outputting to a display device a visual display of the attraction point.