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Tissue-penetrating electrochemical sensor featuring a co-electrodeposited thin film comprised of polymer and bio-recognition element

  • US 10,092,207 B1
  • Filed: 05/09/2017
  • Issued: 10/09/2018
  • Est. Priority Date: 05/15/2016
  • Status: Active Grant
First Claim
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1. A tissue-penetrating electrochemical sensor device for the quantification of a chemical or biochemical entity in a physiological fluid, the device comprising:

  • a tissue-penetrating electrochemical sensor comprising at least one spatially-defined working electrode;

    a conducting polymer film comprising an organic electroactive monomer precursor and at least one biorecognition element, the organic electroactive monomer precursor and the at least one biorecognition element dispersed uniformly and physically entrapped in the conducting polymer film;

    wherein the conducting polymer film is produced by immersing the tissue-penetrating electrochemical sensor in a solution containing the at least one biomolecular recognition element and the organic electroactive monomer precursor which is dissolved in the solution, and wherein application of an oxidizing potential or a reducing potential at the spatially-defined working electrode causes the co-electrodeposition of the conducting polymer film.

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