Method and apparatus to monitor physiologic and biometric parameters using a non-invasive set of transducers
First Claim
1. A system to non-invasively monitor the cardiac cycle of a patient and quantify changes in blood volume of said patient over time therefrom, comprising:
- a phonocardiography transducer configured to measure pressure waves originating from said patient'"'"'s heart function during said cardiac cycle and generate an analog audio signal waveform corresponding to said cardiac cycle;
a data acquisition unit configured to condition said analog audio signal waveform, convert said analog audio signal waveform to digital data, store said digital data, and communicate said digital data;
a processor including a non-transitory computer-readable storage device storing a waveform analysis software module comprising a series of computer-readable instructions for analyzing the signal waveforms by the steps of,automatically identifying and extracting time based heart sound features and heartbeat period from said digital data over a time interval,computing a phonocardiographic systolic time interval (PSTI) metric comprising a function of said extracted time based heart sound features and heart beat period and storing a log of said computed PSTI metric over said time interval;
monitoring said log of said computed PSTI metric over said time interval to establish a baseline and detect changes from said baseline;
andpresenting said changes in PSTI as a surrogate for changes in blood volume to guide therapeutic treatment.
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Abstract
Method and apparatus for quantitative and qualitative determination of heart rate, stroke volume, cardiac output, and central fluid volume. Phonocardiography based technique using multiple transducers and multi-sensor processing algorithms provides a non-invasive method of evaluating the output of the heart. This basic system coupled with additional sensor elements provides a wide range of potential capabilities. A system comprising these techniques in a wearable form provides a non-invasive method of determining hydration status and blood volume status. Phonocardiography augmented with multi-sensor signal processing techniques improves signal quality to analyze heart sounds and associated features (e.g. S1 and S2, amongst others). Noise compensation and cancellation techniques for phonocardiography further improve signal to noise ratio to reject external disturbances.
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Citations
17 Claims
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1. A system to non-invasively monitor the cardiac cycle of a patient and quantify changes in blood volume of said patient over time therefrom, comprising:
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a phonocardiography transducer configured to measure pressure waves originating from said patient'"'"'s heart function during said cardiac cycle and generate an analog audio signal waveform corresponding to said cardiac cycle; a data acquisition unit configured to condition said analog audio signal waveform, convert said analog audio signal waveform to digital data, store said digital data, and communicate said digital data; a processor including a non-transitory computer-readable storage device storing a waveform analysis software module comprising a series of computer-readable instructions for analyzing the signal waveforms by the steps of, automatically identifying and extracting time based heart sound features and heartbeat period from said digital data over a time interval, computing a phonocardiographic systolic time interval (PSTI) metric comprising a function of said extracted time based heart sound features and heart beat period and storing a log of said computed PSTI metric over said time interval; monitoring said log of said computed PSTI metric over said time interval to establish a baseline and detect changes from said baseline; and presenting said changes in PSTI as a surrogate for changes in blood volume to guide therapeutic treatment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification