Extended release of neuregulin for treating heart failure
First Claim
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1. A method for treating heart failure in a mammal, the method comprising administering subcutaneous extended release of neuregulin into a mammal in an amount of 0.3 μ
- g/kg/day to 3.0 μ
g/kg/day, wherein the subcutaneous extended release of neuregulin into a mammal is accomplished through the use of a pump.
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Abstract
The present invention provides methods and kits for preventing, treating or delaying various cardiovascular diseases or disorders especially heart failure by extended release of neuregulin to a mammal. Moreover, the extended release of neuregulin is administered by subcutaneous infusion with a pump.
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Citations
63 Claims
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1. A method for treating heart failure in a mammal, the method comprising administering subcutaneous extended release of neuregulin into a mammal in an amount of 0.3 μ
- g/kg/day to 3.0 μ
g/kg/day, wherein the subcutaneous extended release of neuregulin into a mammal is accomplished through the use of a pump. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63)
- g/kg/day to 3.0 μ
Specification