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Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs

  • US 10,098,987 B2
  • Filed: 10/11/2016
  • Issued: 10/16/2018
  • Est. Priority Date: 07/18/2014
  • Status: Active Grant
First Claim
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1. A catheter comprising:

  • an expandable portion on an elongated body; and

    a first coating over an outer surface of the expandable portion, wherein the first coating comprises;

    a hydrophobic matrix, wherein the hydrophobic matrix comprises a cholesterol and a fatty acid; and

    a dispersed phase comprising a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a biodegradable or bioerodable polymer; and

    wherein at least a portion of the first coating will transfer to a luminal surface when the expandable portion is expanded at a treatment site, and transfers at least a portion of the plurality of micro-reservoirs to the luminal surface.

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