Device and method for detection of counterfeit pharmaceuticals and/or drug packaging

• US 10,101,280 B2
• Filed: 10/24/2016
• Issued: 10/16/2018
• Est. Priority Date: 03/31/2009
• Status: Active Grant

• Current Assignee: United States Department Of Health And Human Services (Government of the United States of America)
• Original Assignee: United States Department Of Health And Human Services (Government of the United States of America)
• Inventors: Ranieri, Nicola, Witkowski, Mark R., Hammaker, Robert, Fateley, William G.
• Primary Examiner(s): Bailey, Frederick D
• Application Number:
  US15/332,908
• Publication Number:
  US 20170038309A1
• Time in Patent Office: 722 Days
• Field of Search: None
• CPC Class Codes: G01J 3/02 Details
• CPC Class Codes: G01J 3/0272 Handheld
• CPC Class Codes: G01J 3/10 Arrangements of light sources specially adapted for spectrometry or colorimetry
• CPC Class Codes: G01J 3/32 Investigating bands of a spectrum in sequence by a single detector
• CPC Class Codes: G01J 3/50 using electric radiation detectors
• CPC Class Codes: G01J 3/501 Colorimeters using spectrally-selective light sources, e.g. LEDs
• CPC Class Codes: G01N 21/27 using photo-electric detection G01N21/31 takes precedence; circuits for computing concentration logarithmic circuits G06G7/24; photometric circuits in general G01J
• CPC Class Codes: G01N 21/33 using ultraviolet light G01N21/39 takes precedence
• CPC Class Codes: G01N 21/3563 for analysing solids; Preparation of samples therefor
• CPC Class Codes: G01N 21/64 Fluorescence; Phosphorescence
• CPC Class Codes: G01N 21/95 characterised by the material or shape of the object to be examined G01N21/89 - G01N21/91, G01N21/94 take precedence
• CPC Class Codes: G01N 21/9508 Capsules; Tablets
• CPC Class Codes: G01N 2201/0221 Portable; cableless; compact; hand-held
• CPC Class Codes: G01N 2201/0627 Use of several LED's for spectral resolution
• CPC Class Codes: G01N 33/15 Medicinal preparations ; Physical properties thereof, e.g. dissolubility
• CPC Class Codes: G06V 10/143 Sensing or illuminating at different wavelengths
• CPC Class Codes: G06V 10/56 relating to colour
• CPC Class Codes: G06V 20/66 Trinkets, e.g. shirt buttons or jewellery items recognising microscopic objects G06V20/69
• CPC Class Codes: G06V 20/80 Recognising image objects characterised by unique random patterns

Abstract

Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect(s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging.

Claims

1. A device for detecting a counterfeit product, comprising:

a plurality of light sources configured to emit light at a plurality of different wavelengths onto a potentially suspect product;

at least one image acquisition device; and

at least one display for observing a color comparison of an image of the potentially suspect product illuminated by the plurality of different wavelengths and an image of a known product under illumination of the same wavelengths.

2. The device of claim 1 further comprising a housing and wherein the plurality of light sources and the at least one image acquisition device are coupled to the housing so that the plurality of light sources and the at least one image acquisition device are maintained in fixed relation to each other while the potentially suspect product is being illuminated.

3. The device of claim 2, wherein the plurality of light sources and the at least one image acquisition device are on a bottom of the housing, and the at least one display is on a top of the housing.

4. The device of claim 1, further comprising a light source control device for controlling respective ones of the light sources.

5. The device of claim 1, further comprising a communication device configured so as to allow communications between the detection device and a device that is external to the detection device.

6. The device of claim 1, wherein the device further comprises two image acquisition devices.

7. The device of claim 1, wherein said image acquisition device includes a colored filter.

8. The device of claim 1, wherein said image acquisition device is a CCD array.

9. The device of claim 1, wherein at least one of the plurality of light sources is configured so as to emit light having an infrared wavelength, at least one of the plurality of light sources is configured so as to emit light having a visible wavelength, and at least one of the plurality of light sources is configured so as to emit light having an ultraviolet wavelength.

10. The device of claim 1, wherein said light sources are LED light sources.

11. The device of claim 1, wherein the at least one image acquisition device includes a macro lens.

12. A device for detecting a counterfeit product, comprising:

a housing;

a plurality of light sources coupled to said housing configured to emit light at a plurality of different wavelengths, wherein said light sources includes at least one infrared wavelength, at least one visible wavelength and at least one ultraviolet wavelength;

at least one image acquisition device for acquiring an image of potentially suspect product illuminated by the plurality of different wavelengths;

at least one display for observing a color comparison of the image of the potentially suspect product illuminated by the plurality of different wavelengths and an image of a known product under illumination of the same wavelengths; and

a plurality of buttons controlling respective ones of said light sources.

13. A method for detecting a counterfeit product, comprising the steps of:

selecting a wavelength or wavelength range of light;

exposing a suspected counterfeit product to light of said selected wavelength or wavelength range with a light source;

viewing a color of said suspected counterfeit product upon exposure to said wavelength or wavelength range;

comparing the color of said suspected counterfeit product exposed to the wavelength or wavelength range to a color of a known product exposed to light of the same wavelength or wavelength range; and

determining a similarity of a composition between the suspected counterfeit product and the known product without viewing a light sensitive marker.

14. The method of claim 13, further comprising wearing colored goggles when viewing the suspected counterfeit product.

15. The method of claim 13, wherein said wavelength is within the visible, ultraviolet or infrared range.

16. The method of claim 13, wherein the suspected counterfeit product and said known product are exposed to said light and viewed simultaneously.

17. The method of claim 13, wherein the appearance of the suspected counterfeit product is compared to an image of the known product exposed to the same wavelength of light.

18. The method of claim 13, wherein said suspected counterfeit product is a tablet, capsule, vial and/or packaging components.

19. The method of claim 13, wherein exposing the suspected counterfeit product to light further comprises turning a plurality of light sources on and off in a predetermined sequence.

20. The method of claim 13, wherein determining the similarity of the composition further comprises detecting a component within the suspected counterfeit product based at least in part on a difference between a color of the suspected counterfeit product and a color of the known product.

21. The method of claim 20, wherein the component is an excipient.

22. The method of claim 20, wherein the color difference between the suspected counterfeit product and the known product is not detectable under ambient lighting conditions.