Basket for a catheter device

• US 10,105,154 B1
• Filed: 11/09/2017
• Issued: 10/23/2018
• Est. Priority Date: 11/09/2017
• Status: Active Grant

• Current Assignee: Thrombolex, Inc.
• Original Assignee: Pebble Hill Partners, LLC
• Inventors: Green, Nicholas
• Primary Examiner(s): Schmidt, Emily
• Application Number:
  US15/808,649
• Time in Patent Office: 348 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 18/245 for removing obstructions in blood vessels or calculi
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/22085 light-absorbing A61B2017/22087 takes precedence
• CPC Class Codes: A61B 2017/22087 photodynamic
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/0041 Removal of thrombosis
• CPC Class Codes: A61B 2018/2211 Plurality of fibres
• CPC Class Codes: A61B 2090/064 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61B 2217/007 with irrigation system
• CPC Class Codes: A61B 5/00 Measuring for diagnostic purposes radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00; Identification of persons
• CPC Class Codes: A61B 5/1076 for measuring dimensions inside body cavities, e.g. using catheters A61B3/1005 takes precedence
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61N 2005/063 comprising light transmitting means, e.g. optical fibres
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent

Abstract

The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.

Claims

1. A basket for an infusion catheter comprising:

a shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end and defining a longitudinal axis, wherein a plurality of helical cuts along a portion of the shaft between the inner and outer surface of the wall form a plurality of tines;

wherein the proximal end of the shaft is uncut;

a plurality of tubes, each tube comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end;

wherein the plurality of tubes are melted together and to the outside of the shaft at the uncut proximal end of the shaft;

wherein each of the plurality of tines of the shaft are disposed in the lumen of each of the plurality of tubes to form a plurality of limbs;

wherein the plurality of tines independently support the limbs without interconnection of tines between the proximal and distal end of the tines; and

wherein the distal end of each of the plurality of limbs are attached together.

2. The basket of claim 1, wherein the limbs of the basket deploy from a first position to a second position when the longitudinal length of the basket is reduced.

3. The basket of claim 2, wherein the limbs of the basket are in a closed state in the first position.

4. The basket of claim 1, wherein the limbs of the basket expand radially away from the longitudinal axis when the longitudinal length of the basket is reduced.

5. The basket of claim 1, wherein the shaft comprises a shape memory material.

6. The basket of claim 5, wherein the shape memory material is a nickel-titanium nitinol alloy.

7. The basket of claim 1, wherein the plurality of cuts are formed by laser cutting.

8. The basket of claim 1, wherein the plurality of helical cuts are helical and have a rotation of at least 360 degrees over the length of the deployable infusion basket.

9. The basket of claim 8, wherein the plurality of helical cuts have a rotation of at least 450 degrees over the length of the deployable infusion basket.

10. The basket of claim 1, wherein each of the plurality of tubes is porous.

11. The basket of claim 10, wherein each of the plurality of tubes comprises a plurality of infusion ports extending between the inner surface and outer surface of the wall of the tube.

12. The basket of claim 11, wherein the infusion ports are holes having diameters between 0.001 and 0.006 inches.

13. The basket of claim 1, wherein the deployable infusion basket is between three and eight inches in length.

14. The basket of claim 1, wherein the deployable infusion basket is about six inches in length.

15. The basket of claim 1, further comprising a fiber optic material disposed within the lumen of at least one of the plurality of tubes.

16. A catheter comprising:

a basket comprising;

a shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end and defining a longitudinal axis, wherein a plurality of helical cuts along at least a portion of the shaft between the inner and outer surface of the wall form a plurality of tines wherein the proximal end of the shaft is uncut;

a plurality of tubes, each tube comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end;

wherein the each of the plurality of tines of the shaft are disposed in the lumen of each of the plurality of tubes to form a plurality of limbs;

wherein the plurality of tines independently support the limbs without interconnection of tines between the proximal and distal end of the tines; and

wherein the distal end of each of the plurality of limbs are attached and the proximal end of each of the plurality of limbs are melted together and to the outside of the shaft;

an inner shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end, wherein the inner shaft is disposed coaxially within the lumen of the shaft and is attached to the distal end of the basket;

an outer shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end, wherein the outer shaft is disposed coaxially around the inner shaft to form a fluid compartment between the inner surface of the outer shaft and the outer surface of the inner shaft; and

wherein the proximal end of the limbs of the basket are connected to the fluid compartment.

17. The catheter of claim 16, wherein the connection between the proximal end of the limbs of the basket and the fluid compartment comprises a seal disposed between the inner shaft and the proximal end of the plurality of limbs.

18. The catheter of claim 16, wherein the limbs of the basket deploy from a first position to a second position when the inner shaft is moved in a proximal direction.

19. The catheter of claim 16, wherein the limbs of the basket expand radially away from the longitudinal axis when the inner shaft is moved in a proximal direction.

20. The catheter of claim 16, wherein each of the plurality of tubes comprises a plurality of infusion ports extending between the inner surface and outer surface of the wall of the tube.

21. The catheter of claim 16, further comprising a fiber optic material disposed within the lumen of the inner shaft or at least one of the plurality of tubes.

22. The catheter of claim 16, wherein the basket further comprises an irradiation source.

23. A method of catheter-directed thrombolysis, the method comprising:

providing a catheter comprising;

a basket comprising;

a shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end and defining a longitudinal axis, wherein a plurality of helical cuts along at least a portion of the shaft between the inner and outer surface of the wall form a plurality of tines, wherein the proximal end of the shaft is uncut;

a plurality of tubes, each tube comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end, wherein the plurality of tubes are melted together and to the outside of the shaft at the uncut proximal end of the shaft, wherein the each of the plurality of tines of the shaft are disposed in the lumen of each of the plurality of tubes to form a plurality of limbs, wherein the plurality of tines independently support the limbs without interconnection of tines between the proximal and distal end of the tines; and

wherein the distal end of each of the plurality of limbs are attached together;

an inner shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end, wherein the inner shaft is disposed coaxially within the lumen of the shaft and is attached to the distal end of the basket;

an outer shaft comprising a wall with an inner surface and an outer surface and a lumen extending between a distal end and a proximal end, wherein the outer shaft is disposed coaxially around the inner shaft to form a fluid compartment between the inner surface of the outer shaft and the outer surface of the inner shaft; and

wherein the proximal end of the limbs of the basket are connected to the fluid compartment;

advancing the basket at least partially through a thrombus within a vessel in a first position;

deploying the basket to a second position; and

simultaneously infusing a therapeutic fluid through the infusion ports of the limbs of the basket.

24. The method of claim 23, wherein the limbs of the basket are in a closed state in the first position and radially expand away from the longitudinal axis in the second position.

25. The method of claim 24, wherein a fluid opening through the thrombus is created when deploying the basket to the second position.

26. The method of claim 23, wherein the therapeutic fluid comprises a thrombolytic agent.

27. The method of claim 23, further comprising delivering light energy to the thrombus.

28. The method of claim 27, wherein the light energy is delivered to the thrombus through a fiber optic material disposed within the lumen of the inner shaft or at least one of the plurality of tubes.

29. The method of claim 27, wherein the light energy is delivered to the thrombus simultaneously with the infusion of the therapeutic fluid.